Haematopoiesis in Zebrafish (Danio Rerio)
Frontiers in Immunology, 2022 Haematopoiesis in fish and mammals is a complex process, and many aspects regarding its model and the differentiation of haematopoietic stem cells (HSCs) still remain enigmatic despite advanced studies.
Michał Stosik +2 more
exaly +5 more sources
Paraspinal extramedullary haematopoiesis in a patient with sickle cell disease: a rare clinical presentation [PDF]
European Journal of Case Reports in Internal MedicineBackground: Extramedullary haematopoiesis refers to the formation of blood cells outside the bone marrow, typically as a compensatory response to chronic anaemia or bone marrow failure.
Anurag Raje +3 more
doaj +2 more sources
RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis [PDF]
EMBO Journal, 2012 Cell fate decisions during haematopoiesis are governed by lineage-specific transcription factors, such as RUNX1, SCL/TAL1, FLI1 and C/EBP family members. To gain insight into how these transcription factors regulate the activation of haematopoietic genes
Rebecca Hannah +2 more
exaly +4 more sources
Faster postnatal decline in hepatic erythropoiesis than granulopoiesis in human newborns [PDF]
Frontiers in PediatricsBackgroundDuring human foetal development, the liver is the primary site of blood cell production, but this activity declines in the third trimester and postnatally as haematopoiesis shifts to bone marrow.
Petra Janovska +14 more
doaj +2 more sources
Optimal experimental design for mathematical models of haematopoiesis. [PDF]
, 2021 The haematopoietic system has a highly regulated and complex structure in which cells are organized to successfully create and maintain new blood cells.
Iniguez, Abdon +9 more
core +1 more source
New light shed on the early evolution of limb-bone growth plate and bone marrow
eLife, 2021 The production of blood cells (haematopoiesis) occurs in the limb bones of most tetrapods but is absent in the fin bones of ray-finned fish. When did long bones start producing blood cells?
Jordi Estefa +6 more
doaj +1 more source
Retinoic acid receptor regulation of decision-making for cell differentiation
Frontiers in Cell and Developmental Biology, 2023 All-trans retinoic acid (ATRA) activation of retinoic acid receptors (RARs) is crucial to an organism’s proper development as established by findings for mouse foetuses from dams fed a vitamin A-deficient diet.
Geoffrey Brown
doaj +1 more source
Journal of Marine Science and Engineering, 2022 The colonial ascidian Botryllus schlosseri possesses an innate immunity, which plays fundamental roles in its survival, adaptability, worldwide spread and ecological success.
Francesca Cima
doaj +1 more source
Zoledronic acid inhibits the growth of leukemic MLL-AF9 transformed hematopoietic cells
Heliyon, 2020 A leukemic in vitro model produced by transducing Cord Blood derived-hematopoietic CD34+ cells with the MLL-AF9 translocation resulting in the oncogenic fusion protein, is used to assess for sensitivity to Zoledronic acid.
Emanuela Chiarella +9 more
doaj +1 more source
Zebrafish Caudal Haematopoietic Embryonic Stromal Tissue (CHEST) Cells Support Haematopoiesis. [PDF]
, 2017 Haematopoiesis is an essential process in early vertebrate development that occurs in different distinct spatial locations in the embryo that shift over time.
Aggio, Julian +6 more
core +1 more source