Results 11 to 20 of about 24,687 (303)
MicroRNAs as Haematopoiesis Regulators
The production of different types of blood cells including their formation, development, and differentiation is collectively known as haematopoiesis.
Ram Babu Undi +2 more
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Vitamin D and Haematopoiesis [PDF]
AbstractPurpose of ReviewThis review examines the influences of active vitamin D on ‘developmental’ haematopoiesis and the immune cells produced. Haematopoiesis gives rise to the platelets, erythrocytes and a wide range of immune cell types each of which performs a specific role to protect the organism from a myriad of infectious agents.
Geoffrey Brown +2 more
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Pulmonary extramedullary haematopoiesis [PDF]
A 72-year-old Caucasian lady with myeloproliferative disorder was admitted for evaluation of progressive dyspnoea, weight loss, fatigue and mild hypoxia. A diffuse ground glass opacity was seen on CT pulmonary angiogram. Differential diagnoses included heart failure, infection, progression of myeloproliferative disorder with extramedullary ...
Veenu, Mubarak +4 more
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Extramedullary haematopoiesis in the kidney [PDF]
Extramedullary haematopoiesis (EMH) is the development of haematopoietic tissue outside the bone marrow and it most often occurs in the liver and spleen. Renal EMH is quite rare and there are very few case reports concerning the kidney. We describe two cases of 'renal histologically documented EMH' and, in particular, in the second of these two, the ...
Ricci, Davide +4 more
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The MLL/SET family and haematopoiesis [PDF]
As demonstrated through early work in Drosophila, members of the MLL/SET family play essential roles during embryonic development through their participation in large protein complexes that are central to epigenetic regulation of gene expression. One of its members, MLL1, has additionally received a lot of attention as it is a potent oncogenic driver ...
Antunes, Eric, Ottersbach, Katrin
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Like in vertebrates, Drosophila haematopoiesis occurs in two waves. It gives rise to three types of haemocytes: plasmatocytes (phagocytosis), crystal cells (melanization) and lamellocytes (encapsulation of parasites). A first population of haemocytes, specified during embryogenesis, gives rise to an invariant number of plasmatocytes and crystal cells ...
Michèle, Crozatier, Marie, Meister
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The histone H3K4 demethylase JARID1A directly interacts with haematopoietic transcription factor GATA1 in erythroid cells through its second PHD domain [PDF]
Chromatin remodelling and transcription factors play important roles in lineage commitment and development through control of gene expression. Activation of selected lineage-specific genes and repression of alternative lineage-affiliated genes results in
Biasutto, Antonio J +4 more
core +1 more source
Monocytes, Macrophages, and Metabolic Disease in Atherosclerosis
Atherosclerotic cardiovascular disease (CVD) is a lipid-driven chronic inflammatory disease, in which macrophages are responsible for taking up these lipids and driving disease progression.
Michelle C. Flynn +4 more
doaj +1 more source
GATA2 mitotic bookmarking is required for definitive haematopoiesis
In mitosis, most transcription factors detach from chromatin, but some are retained and bookmark genomic sites. Mitotic bookmarking has been implicated in lineage inheritance, pluripotency and reprogramming.
Rita Silvério-Alves +14 more
doaj +1 more source
Haemogenic endocardium contributes to transient definitive haematopoiesis. [PDF]
Haematopoietic cells arise from spatiotemporally restricted domains in the developing embryo. Although studies of non-mammalian animal and in vitro embryonic stem cell models suggest a close relationship among cardiac, endocardial and haematopoietic ...
Arshi, Armin +14 more
core +1 more source

