Results 11 to 20 of about 24,687 (303)

MicroRNAs as Haematopoiesis Regulators

open access: yesAdvances in Hematology, 2013
The production of different types of blood cells including their formation, development, and differentiation is collectively known as haematopoiesis.
Ram Babu Undi   +2 more
doaj   +3 more sources

Vitamin D and Haematopoiesis [PDF]

open access: yesCurrent Tissue Microenvironment Reports, 2020
AbstractPurpose of ReviewThis review examines the influences of active vitamin D on ‘developmental’ haematopoiesis and the immune cells produced. Haematopoiesis gives rise to the platelets, erythrocytes and a wide range of immune cell types each of which performs a specific role to protect the organism from a myriad of infectious agents.
Geoffrey Brown   +2 more
openaire   +1 more source

Pulmonary extramedullary haematopoiesis [PDF]

open access: yesBMJ Case Reports, 2011
A 72-year-old Caucasian lady with myeloproliferative disorder was admitted for evaluation of progressive dyspnoea, weight loss, fatigue and mild hypoxia. A diffuse ground glass opacity was seen on CT pulmonary angiogram. Differential diagnoses included heart failure, infection, progression of myeloproliferative disorder with extramedullary ...
Veenu, Mubarak   +4 more
openaire   +2 more sources

Extramedullary haematopoiesis in the kidney [PDF]

open access: yesClinical Kidney Journal, 2012
Extramedullary haematopoiesis (EMH) is the development of haematopoietic tissue outside the bone marrow and it most often occurs in the liver and spleen. Renal EMH is quite rare and there are very few case reports concerning the kidney. We describe two cases of 'renal histologically documented EMH' and, in particular, in the second of these two, the ...
Ricci, Davide   +4 more
openaire   +2 more sources

The MLL/SET family and haematopoiesis [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2020
As demonstrated through early work in Drosophila, members of the MLL/SET family play essential roles during embryonic development through their participation in large protein complexes that are central to epigenetic regulation of gene expression. One of its members, MLL1, has additionally received a lot of attention as it is a potent oncogenic driver ...
Antunes, Eric, Ottersbach, Katrin
openaire   +2 more sources

Drosophila haematopoiesis

open access: yesCellular Microbiology, 2007
Like in vertebrates, Drosophila haematopoiesis occurs in two waves. It gives rise to three types of haemocytes: plasmatocytes (phagocytosis), crystal cells (melanization) and lamellocytes (encapsulation of parasites). A first population of haemocytes, specified during embryogenesis, gives rise to an invariant number of plasmatocytes and crystal cells ...
Michèle, Crozatier, Marie, Meister
openaire   +2 more sources

The histone H3K4 demethylase JARID1A directly interacts with haematopoietic transcription factor GATA1 in erythroid cells through its second PHD domain [PDF]

open access: yes, 2020
Chromatin remodelling and transcription factors play important roles in lineage commitment and development through control of gene expression. Activation of selected lineage-specific genes and repression of alternative lineage-affiliated genes results in
Biasutto, Antonio J   +4 more
core   +1 more source

Monocytes, Macrophages, and Metabolic Disease in Atherosclerosis

open access: yesFrontiers in Pharmacology, 2019
Atherosclerotic cardiovascular disease (CVD) is a lipid-driven chronic inflammatory disease, in which macrophages are responsible for taking up these lipids and driving disease progression.
Michelle C. Flynn   +4 more
doaj   +1 more source

GATA2 mitotic bookmarking is required for definitive haematopoiesis

open access: yesNature Communications, 2023
In mitosis, most transcription factors detach from chromatin, but some are retained and bookmark genomic sites. Mitotic bookmarking has been implicated in lineage inheritance, pluripotency and reprogramming.
Rita Silvério-Alves   +14 more
doaj   +1 more source

Haemogenic endocardium contributes to transient definitive haematopoiesis. [PDF]

open access: yes, 2013
Haematopoietic cells arise from spatiotemporally restricted domains in the developing embryo. Although studies of non-mammalian animal and in vitro embryonic stem cell models suggest a close relationship among cardiac, endocardial and haematopoietic ...
Arshi, Armin   +14 more
core   +1 more source

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