Results 141 to 150 of about 751,739 (361)
Stem Cell Activation in Adult Organisms [PDF]
International Journal of Molecular Sciences, 2016 Stem cells are responsible for the organ and tissue development, growth and maintenance from embryonic stage up to late adult life.[...]
openaire +3 more sources
Molecular Oncology, EarlyView.Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon +13 more
wiley +1 more source
Stem Cell Research & TherapyBackground Peripheral arterial disease (PAD) is a leading cause of limb disability due to ischemia caused by atherosclerotic plaques. Cell-based therapies using endothelial cells (ECs) have shown promise in promoting angiogenesis for PAD, but challenges ...
Jungju Choi +7 more
doaj +1 more source
Potensi Terapi Sel Punca Dalam Dunia Kedokteran Dan Permasalahannya [PDF]
, 2008 Stem cell has become a main focus for not only reseacrhers but also society due to its potency in cell-based therapy. Regardless ethical issues surrounding the human embryonic stem cell, adult human stem cell became the alternative of choice for ...
Aini, N. (Nurul) +4 more
core
Expression of c-kit and stem cell factor mRNA in liver specimens from healthy adult dogs [PDF]
, 1998 Masahiro Morimoto +4 more
openalex +1 more source
Molecular Oncology, EarlyView.Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo +11 more
wiley +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Regulation of adult stem cell function by ketone bodies. [PDF]
Front Cell Dev Biol, 2023 Andersen OE +3 more
europepmc +1 more source
Adult Spinal Cord Stem Cells Generate Neurons after Transplantation in the Adult Dentate Gyrus [PDF]
, 2000 Lamya S. Shihabuddin +3 more
openalex +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source