Results 151 to 160 of about 797,049 (362)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Adult Human Mesenchymal Stem Cell Differentiation to the Osteogenic or Adipogenic Lineage Is Regulated by Mitogen-activated Protein Kinase [PDF]
, 2000 Rama K. Jaiswal +5 more
openalex +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Regulation of adult stem cell function by ketone bodies. [PDF]
Front Cell Dev Biol, 2023 Andersen OE +3 more
europepmc +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
IL-12 and Related Cytokines: Function and Regulatory Implications in Candida albicans Infection
Clinical and Developmental Immunology, 2011 IL-12 is a cytokine with links to both innate and adaptive immunity systems. In mice, its deletion leads to acute susceptibility to oral infection with the yeast Candida albicans, whereas such mice are resistant to systemic disease.
Robert B. Ashman +2 more
doaj +1 more source
Adult Spinal Cord Stem Cells Generate Neurons after Transplantation in the Adult Dentate Gyrus [PDF]
, 2000 Lamya S. Shihabuddin +3 more
openalex +1 more source
Investigation of growth factors and cytokines that suppress adult stem cell asymmetric cell kinetics [PDF]
, 2005 Thesis (S.M.)--Massachusetts Institute of Technology, Biological Engineering Division, 2005.Includes bibliographical references (leaves 40-43).Adult stem cells are potentially useful in many biomedical applications that can save lives and increase the ...
Ganz, Michal
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Case Reports in Transplantation, 2012 Acinetobacter baumannii is a gram-negative, nonfermentative coccobacillus that causes infections in immunocompromised and chronically ill patients and is associated with multidrug resistance.
Khalid Ahmed Al-Anazi +6 more
doaj +1 more source