Results 11 to 20 of about 820,702 (356)

Risk assessment for newly diagnosed, fit and young patients with Multiple Myeloma, in the era of novel treatment modalities: Are there any additional factors to be under consideration?

open access: yesHematology, Transfusion and Cell Therapy, 2022
Objective: Multiple myeloma (MM) is considered a disease of elderlies however, 35-40% of newly diagnosed MM (NDMM) patients (pts) are ≤60 years (ys) old.
Panayotis Kaloyannidis   +6 more
doaj   +1 more source

Adult stem cells [PDF]

open access: yesThe FASEB Journal, 2003
Adult tissues contain a continuum of precursor cells, ranging from very primitive stem cells to tissue‐committed progenitor cells. The very primitive stem cells have essentially an unlimited proliferation potential and will form all cell types of the body.
Henry E, Young, Asa C, Black
openaire   +2 more sources

Repeated courses of escalating doses of Nivolumab in refractory Hodgkin lymphoma with recurrent relapses post allografting: A safe and effective treatment approach

open access: yesHematology Reports, 2021
For patients with Hodgkin Lymphoma (HL) who experience relapse post allogeneic stem cell transplantation, limited treatment options exist, and the ultimate outcome is poor.
Panayotis Kaloyannidis   +4 more
doaj   +1 more source

Tracking adult stem cells [PDF]

open access: yesEMBO reports, 2011
The maintenance of stem‐cell‐driven tissue homeostasis requires a balance between the generation and loss of cell mass. Adult stem cells have a close relationship with the surrounding tissue—known as their niche—and thus, stem‐cell studies should preferably be performed in a physiological context, rather than outside their natural environment.
Snippert HJ, Clevers H.
openaire   +2 more sources

Adult stem cell plasticity [PDF]

open access: yesThe Journal of Pathology, 2002
AbstractObservations made in the last few years support the existence of pathways, in adult humans and rodents, that allow adult stem cells to be surprisingly flexible in their differentiation repertoires. Termed plasticity, this property allows adult stem cells, assumed, until now, to be committed to generating a fixed range of progeny, to switch ...
Richard, Poulsom   +3 more
openaire   +2 more sources

Adult stem cells.

open access: yesIssues in law & medicine, 2004
One of the fields of medicine that has created the greatest expectations in recent years is cellular therapy with stem cells. The isolation of human embryo cells, the apparent and unexpected potential of adult stem cells, and the development of gene therapy lead us to imagine a hopeful future for a significant number of diseases that are at present ...
F, Prósper, C M, Verfaillie
  +8 more sources

Subventricular zone stem cells are heterogeneous with respect to their embryonic origins and neurogenic fates in the adult olfactory bulb [PDF]

open access: yes, 2007
Wedetermined the embryonic origins of adult forebrain subventricular zone (SVZ) stem cells by Cre-lox fate mapping in transgenic mice. We found that all parts of the telencephalic neuroepithelium, including the medial ganglionic eminence and lateral ...
C.H. Papadimitriou   +8 more
core   +4 more sources

Establishing a 3D In Vitro Hepatic Model Mimicking Physiologically Relevant to In Vivo State

open access: yesCells, 2021
Three-dimensional (3D) bioprinting is a promising technology to establish a 3D in vitro hepatic model that holds great potential in toxicological evaluation.
Hyun Kyoung Kang   +10 more
doaj   +1 more source

SARS-CoV-2 entry sites are present in all structural elements of the human glossopharyngeal and vagal nerves: Clinical implications

open access: yesEBioMedicine, 2022
Summary: Background: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infections result in the temporary loss of smell and taste in about one third of confirmed cases.
Lynn Vitale-Cross   +4 more
doaj   +1 more source

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