Results 11 to 20 of about 797,049 (362)
Embryonic and Adult Stem Cells [PDF]
Acta Veterinaria Scandinavica, 2004 Ole Johan Borge
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The FASEB Journal, 2003 AbstractDevelopment of a multicellular organism is accomplished through a series of events that are preprogrammed in the genome. These events encompass cellular proliferation, lineage commitment, lineage progression, lineage expression, cellular inhibition, and regulated apoptosis. The sequential progression of cells through these events results in the
Asa C. Black, Henry E. Young
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Tracking adult stem cells [PDF]
EMBO reports, 2011 The maintenance of stem‐cell‐driven tissue homeostasis requires a balance between the generation and loss of cell mass. Adult stem cells have a close relationship with the surrounding tissue—known as their niche—and thus, stem‐cell studies should preferably be performed in a physiological context, rather than outside their natural environment.
Snippert HJ, Clevers H.
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Plasticity of Adult Stem Cells [PDF]
Cell, 2004 Recent years have seen much excitement over the possibility that adult mammalian stem cells may be capable of differentiating across tissue lineage boundaries, and as such may represent novel, accessible, and very versatile effectors of therapeutic tissue regeneration.
Irving L. Weissman, Amy J. Wagers
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Adult stem cells in the endometrium [PDF]
Molecular Human Reproduction, 2010 Rare cells with adult stem cell activity were recently discovered in human endometrium. Endometrial stem/progenitor cell candidates include epithelial, mesenchymal and endothelial cells, and all may contribute to the rapid endometrial regeneration following menstruation, rather than a single candidate. Endometrial mesenchymal stem-like cells (eMSC) are
Hirotaka Masuda, Caroline E. Gargett
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Circulation Research, 2019 Within just a few years, the possibility that the human body contains cells that can repair and regenerate damaged and diseased tissue has gone from an unlikely proposition to a virtual certainty. Adult stem cells have been isolated from numerous adult tissues, umbilical cord, and other non-embryonic sources, and have demonstrated a surprising ability ...
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Adult Stem Cells and Cancer [PDF]
Cancer Research, 2005 To the Editor: Rubio et al. ( [1][1]) reported in Cancer Research that adipose tissue–derived stem cells acquired a transformed phenotype after long-term culture in vitro . This article has been cited together with our article published in the same issue ( [2][2]) as evidence for the ...
Kassem M +3 more
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Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12
Nature Communications, 2021 The tumor suppressor FBW7 is a substrate adaptor for the E3 ubiquitin ligase complex SKP1-CUL1-F-box (SCF) and itself a target for ubiquitylation. Here, the authors show that TRIP12 mediates branched K11-linked ubiquitylation of FBW7, to regulate its ...
Omar M. Khan +8 more
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Rac1 drives intestinal stem cell proliferation and regeneration [PDF]
, 2013 Adult stem cells are responsible for maintaining the balance between cell proliferation and differentiation within self-renewing tissues. The molecular and cellular mechanisms mediating such balance are poorly understood.
Alessandro Scopelliti +28 more
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Journal of Personalized Medicine, 2022 Aging process is associated with numerous intrinsic and extrinsic factors that contribute to the adipose tissue accumulation, atherosclerosis, immune system failures, bone fragility, and cancer [...]
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