Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe+4 more
wiley +1 more source
Reduced adult stem cell fate specification led to eye reduction in cave planarians. [PDF]
Saad LO+4 more
europepmc +1 more source
The Human Fetal and Adult Stem Cell Secretome Can Exert Cardioprotective Paracrine Effects against Cardiotoxicity and Oxidative Stress from Cancer Treatment. [PDF]
Villa F+17 more
europepmc +1 more source
Transplanted adult hematopoietic stems cells differentiate into functional endothelial cells [PDF]
Alexis S. Bailey+7 more
openalex +1 more source
The regenerative potential of adipose tissue‐derived stem cells can be enhanced through chemical stimulation in vitro. A short stimulation protocol using forskolin, either alone or in combination with other growth factors, under xeno‐free conditions enhanced the pro‐angiogenic responses in human ASCs.
Maria Vittoria Giraudo+5 more
wiley +1 more source
Increased levels of lagging strand polymerase α in an adult stem cell lineage affect replication-coupled histone incorporation. [PDF]
Davis BEM+6 more
europepmc +1 more source
The small intestine as a model for evaluating adult tissue stem cell drug targets1 [PDF]
Christopher S. Potten+2 more
openalex +1 more source
LIN28B Promotes Cancer Cell Dissemination and Angiogenesis
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo+8 more
wiley +1 more source
In Vitro Evaluation of the Safety and Efficacy of Cibisatamab Using Adult Stem Cell-Derived Organoids and Colorectal Cancer Spheroids. [PDF]
Anstett V+9 more
europepmc +1 more source