Results 21 to 30 of about 739,663 (341)
SALL4 Expression in Gonocytes and Spermatogonial Clones of Postnatal Mouse Testes [PDF]
, 2013 The spermatogenic lineage is established after birth when gonocytes migrate to the basement membrane of seminiferous tubules and give rise to spermatogonial stem cells (SSC). In adults, SSCs reside within the population of undifferentiated spermatogonia (
A Buageaw +48 more
core +8 more sources
Attributes of adult stem cells [PDF]
The Journal of Pathology, 2008 AbstractWhile cultured embryonic stem (ES) cells can be harvested in abundance and appear to be the most versatile of cells for regenerative medicine, adult stem cells also hold promise, but the identity and subsequent isolation of these comparatively rare cells remains problematic in most tissues, perhaps with the notable exception of the bone marrow.
S Islam, M R Alison
openaire +2 more sources
Hematology, Transfusion and Cell Therapy, 2022 Objective: Patients (pts) who have undergone allogeneic stem cell transplantation (alloSCT) are at high-risk for life-threating complications post SARS-CoV-2 infection, and the mortality rates has been reported of approximately 30-35%.
Panayotis Kaloyannidis +6 more
doaj +1 more source
Experimental and Molecular Medicine, 2018 Stem cell therapy: Finding the best cells Stem cells from some donors have a stronger therapeutic effect than others, and can be identified by genetic markers.
Insung Kang +12 more
doaj +1 more source
Experimental Hematology & Oncology, 2017 Background Ruxolitinib is a potent inhibitor of JAK1/2 with proven efficacy in myelofibrosis. In recent years, research in graft versus host disease (GVHD) has revealed the role of activation of JAK pathways in alloreactive lymphocytes. Some reports have
Mauricio Sarmiento Maldonado +7 more
doaj +1 more source
Zika virus infection accelerates Alzheimer’s disease phenotypes in brain organoids
Cell Death Discovery, 2022 Alzheimer’s disease (AD) is one of the progressive neurodegenerative diseases characterized by β-amyloid (Aβ) production and Phosphorylated-Tau (p-Tau) protein in the cerebral cortex. The precise mechanisms of the cause, responsible for disease pathology
Seung-Eun Lee +9 more
doaj +1 more source
Experimental and Molecular Medicine, 2018 Aging: Clues in nuclear proteins Abnormal versions of proteins that support the structure and function of the membrane of the cell nucleus are implicated in premature aging disorders, and also in normal aging.
Jin Young Lee +9 more
doaj +1 more source
Human iNSC-derived brain organoid model of lysosomal storage disorder in Niemann–Pick disease type C
Cell Death and Disease, 2020 Recent studies on developing three-dimensional (3D) brain organoids from stem cells have allowed the generation of in vitro models of neural disease and have enabled the screening of drugs because these organoids mimic the complexity of neural tissue ...
Seung-Eun Lee +6 more
doaj +1 more source
Stem Cell Research & Therapy, 2021 Background Human mesenchymal stem cells (hMSCs) therapy has recently been considered a promising treatment for atopic dermatitis (AD) due to their immunomodulation and tissue regeneration ability.
Nari Shin +9 more
doaj +1 more source
Intestinal stem cell proliferation and epithelial homeostasis in the adult Drosophila midgut [PDF]
, 2015 Adult tissue homeostasis requires a tight balance between the removal of old or damaged cells and the production of new ones. Such processes are usually driven by dedicated stem cells that reside within specific tissue locations or niches.
Carroll, Lynsey +2 more
core +1 more source