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Adult Neural Stem Cells

2008
Neural stem cells (NSCs) have been identified in the mature central nervous system (CNS), and they reside in specific areas. Cultures of NSCs can be successfully established in vitro by exploiting the NeuroSphere assay. This methodology relies on the continuous exposure of neural cells to mitogens such as epidermal growth factor and fibroblast growth ...
Galli, R   +2 more
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Adult Stem Cells: Adult Skeletal Muscle Stem Cells

2013
Maintenance, repair and regeneration of adult skeletal muscle are mediated by stem or precursor cells within the muscle. In addition to the satellite cell, which is the archetypal muscle stem cell, there are other stem cells within skeletal muscle that can contribute to muscle regeneration under experimental conditions.
Jinhong Meng, Jennifer E. Morgan
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Stem Cells, Adult

2021
Stem cells refer to adult or somatic stem cells obtained from adult body tissues. They are found in the body from the earliest days (3–4 days) of embryonic development and endure throughout the lifecycle, although they are rare, dispersed, and difficult to identify.
Henk ten Have   +1 more
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Stem Cells, Adult

2006
Stem cells are responsible for providing a source of differentiated cells in adult tissues that undergo renewal or repair. Considerable progress has been made recently in the identification and characterization of stem cells in adults. They have been the focus of intense interest because of their potential therapeutic use in restoring form and function
Jason H. Pomerantz   +2 more
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Neuronal stem cells in adults

Experimental Gerontology, 2006
Neuronal stem cells are like other tissue-specific stem cells, undifferentiated cells which can proliferate and may give rise to glia and neurons. They are present in mammalians throughout the entire life and are supposed to play an important role in renewal of neurons.
Hans-Christian, Bauer   +3 more
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Adult-Derived Pluripotent Stem Cells

World Neurosurgery, 2014
The global incidence of spinal cord injury (SCI) is 15-40 cases per million people, with the socioeconomic and healthcare costs amounting to nearly $10 billion per annum in the USA alone. Despite substantial advances in medical care and surgical technology, many patients with SCI still experience significant long-term neurologic disability.
Stuart D, Faulkner   +2 more
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Disguising adult neural stem cells

Current Opinion in Neurobiology, 2004
A description of adult neural stem cells has remained somewhat elusive. With no unique and definitive markers to label stem cells in general, neural stem cells are difficult to identify definitively and one is forced to examine cell behavior - leading to the retrospective identification of a stem cell.
Cindi M, Morshead, Derek, van der Kooy
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Adult Pituitary Stem Cells

2013
Underlying mechanisms leading to pituitary plasticity by which the gland adapts the number of hormone-producing cell to the continuously changing physiological requirements are still poorly understood. Adult stem cells were shown to direct homeostatic cell maintenance, regeneration, and functional plasticity in several organs and tissues. Only recently
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Adult haematopoietic stem cell niches

Nature Reviews Immunology, 2017
Stem cell niches are specialized microenvironments that promote the maintenance of stem cells and regulate their function. Recent advances have improved our understanding of the niches that maintain adult haematopoietic stem cells (HSCs). These advances include new markers for HSCs and niche cells, systematic analyses of the expression patterns of ...
Genevieve M, Crane   +2 more
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Adult hemopoietic stem cell transplantation

The Journal of the American Dental Association, 2003
Hemopoietic stem cell transplantation, or HSCT, is an important tool in modern cancer treatment. Refinement of transplantation techniques and supportive care has resulted in increased posttransplantation survival rates. Dental care is a key supportive element in both pretransplantation and posttransplantation care of this patient population.The authors
Steven D, Westbrook   +2 more
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