Results 31 to 40 of about 407,994 (322)
International Journal of Cell Biology, 2009 Mesenchymal stem cells or multipotent mesenchymal stromal cells (both referred to as MSC) have been shown in some studies to have a beneficial effect on myocardial recovery after infarct.
Katarina Kollar +3 more
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USP7 controls NGN3 stability and pancreatic endocrine lineage development
Nature Communications, 2023 Understanding the factors and mechanisms involved in beta-cell development will guide therapeutic efforts to generate fully functional beta cells for diabetes.
Teodora Manea +6 more
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Modeling of Hypoxic Brain Injury through 3D Human Neural Organoids
Cells, 2021 Brain organoids have emerged as a novel model system for neural development, neurodegenerative diseases, and human-based drug screening. However, the heterogeneous nature and immature neuronal development of brain organoids generated from pluripotent ...
Min Soo Kim +5 more
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Evolutionary dynamics of adult stem cells: Comparison of random and immortal strand segregation mechanisms [PDF]
, 2004 This paper develops a point-mutation model describing the evolutionary dynamics of a population of adult stem cells. Such a model may prove useful for quantitative studies of tissue aging and the emergence of cancer. We consider two modes of chromosome segregation: (1) Random segregation, where the daughter chromosomes of a given parent chromosome ...
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Neural Stem Cells and Neurogenesis in the Adult [PDF]
Cell Stem Cell, 2012 Research in the field of adult neurogenesis has seen substantial progress over recent years. Here we discuss some of the major focus areas for future investigation: neural stem cell heterogeneity, the role of latent stem cells, and the extent of neurogenesis in the adult human brain.
Göritz C, Frisén J.
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Isolation and Characterization of Antler-Derived Multipotent Stem Cells
Cell Transplantation, 2014 Recent studies have reported that stem cells can be isolated from various tissues such as bone marrow, fatty tissue, umbilical cord blood, Wharton's jelly, and placenta. These types of stem cell studies have also arisen in veterinary medicine.
Min-Soo Seo +5 more
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Application of Adult Stem Cells in Medicine [PDF]
Stem Cells International, 2015 For any disease condition, there are two possible approaches to treatment. Treatment approaches that alleviate or suppress the disease condition are the most widespread available options for majority of diseases. This type of treatment is often applied in the form of drugs (chemical or biological) with or without surgical intervention.
Pritha Ray +3 more
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Cell Reports, 2015 A recent study has suggested that fibroblasts can be converted into mouse-induced neural stem cells (miNSCs) through the expression of defined factors. However, successful generation of human iNSCs (hiNSCs) has proven challenging to achieve.
Kyung-Rok Yu +15 more
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NEDD4-1 deficiency impairs satellite cell function during skeletal muscle regeneration
Biological Research, 2023 Background Satellite cells are tissue-specific stem cells primarily responsible for the regenerative capacity of skeletal muscle. Satellite cell function and maintenance are regulated by extrinsic and intrinsic mechanisms, including the ubiquitin ...
Felipe Cabezas +6 more
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A Computational Model Incorporating Neural Stem Cell Dynamics Reproduces Glioma Incidence across the Lifespan in the Human Population [PDF]
Bauer, Roman, Marcus Kaiser, and Elizabeth Stoll. "A Computational
Model Incorporating Neural Stem Cell Dynamics Reproduces Glioma Incidence
across the Lifespan in the Human Population." PloS one 9.11 (2014): e111219, 2015 Glioma is the most common form of primary brain tumor. Demographically, the risk of occurrence increases until old age. Here we present a novel computational model to reproduce the probability of glioma incidence across the lifespan. Previous mathematical models explaining glioma incidence are framed in a rather abstract way, and do not directly relate
arxiv +1 more source