Results 121 to 130 of about 4,970 (302)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Test de respiración única para la capacidad de difusión de monóxido de carbono (DLCO) y su interpretación en enfermedades autoinmunes [PDF]
, 2012 El Test de respiración única para la capacidad de difusión de monóxido de carbono(DLCO) tiene una larga historia desde su nacimiento por Krogh y Krogh en 1909 hasta la primera publicación, describiendo una técnica estandarizada para la medición de la ...
Bello Gualtero, Juan Manuel +1 more
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Tissue distribution, antigen specificity and effector functions of γδ T cells in human diseases [PDF]
, 2018 Conclusions: In conclusion, the large number of studies on human γδ T cells have shown that these lymphocytes share several characteristics in common with αβ T cells, and also embody many unique properties.
De Libero, Gennaro
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Elevated serum levels of checkpoint molecules in patients with adult Still's disease. [PDF]
Arthritis Res Ther, 2020 Fujita Y +11 more
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Case Report: Adult Still's Disease in an Alemtuzumab-Treated Multiple Sclerosis Patient. [PDF]
Front Immunol, 2020 Krämer J +6 more
europepmc +1 more source
Still\u27s Disease in Adults [PDF]
, 1974 In 1897, Dr. George F. Still described 22 children with a form of chronic joint disease which differed from rheumatic fever. Twelve of these children had a syndrome characterized by glandular and splenic enlargement which, with a characteristic fever ...
Edwards, William M. +2 more
core +1 more source