Results 11 to 20 of about 170,479 (217)

Development of a modified prognostic index for patients with aggressive adult T-cell leukemia-lymphoma aged 70 years or younger: possible risk-adapted management strategies including allogeneic transplantation

Haematologica, 2017
Adult T-cell leukemia-lymphoma is a distinct type of peripheral T-cell lymphoma caused by human T-cell lymphotropic virus type I. Although allogeneic stem cell transplantation after chemotherapy is a recommended treatment option for patients with ...
Shigeo Fuji, Takuhiro Yamaguchi, Yoshitaka Inoue, Atae Utsunomiya, Yukiyoshi Moriuchi, Kaoru Uchimaru, Satsuki Owatari, Takashi Miyagi, Jun Taguchi, Ilseung Choi, Eiichi Otsuka, Sawako Nakachi, Hisashi Yamamoto, Saiko Kurosawa, Kensei Tobinai, Takahiro Fukuda   +15 more
doaj   +1 more source

Adult T Cell Leukemia / Lymphoma in Chile

Estudios Atacameños, 1998
Se describen las características clínicas y de laboratorio de 26 pacientes chilenos caucásicos, con leucemia/lymphoma T del adulto, asociado a HTLV- 1 (LLTA).
María Elena Cabrera, Silvia Labra, Anthony Ford, Estrella Matutes   +3 more
doaj   +1 more source

Molecular Hallmarks of Adult T Cell Leukemia

Frontiers in Microbiology, 2012
The molecular hallmarks of adult T cell leukemia (ATL) comprise outstanding deregulations of signaling pathways that control the cell cycle, resistance to apoptosis, and proliferation of leukemic cells, all of which have been identified by early ...
Makoto eYamagishi, Toshiki eWatanabe
doaj   +1 more source

Novel Treatments of Adult T Cell Leukemia Lymphoma

Frontiers in Microbiology, 2020
Adult T cell leukemia-lymphoma (ATL) is an aggressive malignancy secondary to chronic infection with the human T cell leukemia virus type I (HTLV-I) retrovirus. ATL carries a dismal prognosis.
Hiba El Hajj, Kunihiro Tsukasaki, Morgane Cheminant, Morgane Cheminant, Ali Bazarbachi, Ali Bazarbachi, Toshiki Watanabe, Olivier Hermine, Olivier Hermine   +8 more
doaj   +1 more source

Human T cell leukemia virus reactivation with progression of adult T-cell leukemia-lymphoma.

PLoS ONE, 2009
BackgroundHuman T-cell leukemia virus-associated adult T-cell leukemia-lymphoma (ATLL) has a very poor prognosis, despite trials of a variety of different treatment regimens.
Lee Ratner, William Harrington, Xuan Feng, Christian Grant, Steve Jacobson, Ariela Noy, Joseph Sparano, Jeannette Lee, Richard Ambinder, Nancy Campbell, Michael Lairmore, AIDS Malignancy Consortium   +11 more
doaj   +1 more source

Endocrine and metabolic disorders in HTLV-1 infected patients

Brazilian Journal of Infectious Diseases, 2010
Human T-cell leukemia virus type 1 (HTLV-1) infection is endemic in Japan and several countries in South America, Caribbean and Africa. Endocrine and metabolic disorders have been variably reported to be associated with human T-cell leukemia virus type 1
Cresio Alves, MD, PhD, Luciano Dourado, MD   +1 more
doaj   +1 more source

Adult T-Cell Leukemia/Lymphoma with CLL-Like Morphology—A Case Report

Case Reports in Medicine, 2010
Adult T-cell Leukemia/Lymphoma (ATL) is rarely seen in the U.S. and Europe, usually limited to African Americans from the southeastern U.S. and immigrants from HTLV-1 endemic areas.
Nishant Tageja, Mobayed Mohammad, Gail Bentley, Carter Bishop   +3 more
doaj   +1 more source

A rare presentation of adult T-cell leukemia/lymphoma with generalized cutaneous purpuric lesions

Dermatologica Sinica, 2015
Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy caused by human T-cell lymphotropic virus type 1. The disease is characterized by the presence of pleomorphic lymphocytes and cutaneous purpuric eruptions with skin, lymph node, visceral ...
De-En Kao, Chih-Pin Chen, Kan-Tang Fang, Yung-Hsiang Hsu, Sung-Jen Hung   +4 more
doaj   +1 more source

Spectrum of mutational signatures in T-cell lymphoma reveals a key role for UV radiation in cutaneous T-cell lymphoma

Scientific Reports, 2021
T-cell non-Hodgkin’s lymphomas develop following transformation of tissue resident T-cells. We performed a meta-analysis of whole exome sequencing data from 403 patients with eight subtypes of T-cell non-Hodgkin’s lymphoma to identify mutational ...
Christine L. Jones, Andrea Degasperi, Vieri Grandi, Tauanne D. Amarante, Genomics England Research Consortium, Tracey J. Mitchell, Serena Nik-Zainal, Sean J. Whittaker   +7 more
doaj   +1 more source

Leucemia/linfoma T del adulto en pacientes infectados con HTLV-1: reporte de dos casos de Colombia

Biomédica: revista del Instituto Nacional de Salud, 2013
La leucemia/linfoma de células T del adulto (Adult T-Cell Leukemia/Lymphoma, ATLL) es una neoplasia maligna de los linfocitos T CD4 maduros, que resulta de la infección con el virus T-linfotrópico humano de tipo 1 (HTLV-1), con varias manifestaciones ...
Edwin Abraham Medina, Rocío Orduz, Olga Lucía Morales, Óscar Martínez, Margarita Baldión, Mario Arturo Isaza   +5 more
doaj   +1 more source