Results 61 to 70 of about 4,221,129 (325)

The adult vaccination landscape in the United States during the Affordable Care Act era: Results from a large retrospective database analysis.

open access: yesVaccine, 2020
BACKGROUND Early provisions of the Affordable Care Act (ACA) reduced financial barriers to preventive care, including routinely recommended vaccines; however, vaccination coverage remains suboptimal.
E. Aris   +5 more
semanticscholar   +1 more source

Protection against pertussis in humans correlates to elevated serum antibodies and memory B cells [PDF]

open access: yes, 2017
Pertussis is a respiratory infection caused by Bordetella pertussis that may be particularly severe and even lethal in the first months of life when infants are still too young to be vaccinated. Adults and adolescents experience mild symptoms and are the
Carsetti, Rita   +13 more
core   +1 more source

Perceptions of vaccine preventable diseases in Australian healthcare: focus on pertussis

open access: yesHuman Vaccines & Immunotherapeutics, 2021
Adult vaccination in Australia is suboptimal. For instance, as few as one in nine people have received a pertussis vaccine in adolescence or adulthood, despite increasing disease burden and evidence of a positive correlation between older age and ...
Julianne Bayliss   +6 more
doaj   +1 more source

Smallpox and Bioterrorism: Why the Plan to Protect the Nation Is Stalled and What to Do [PDF]

open access: yes, 2003
The Iraq war is over, no weapons of mass destruction (WMD) have yet been found, and the president's smallpox plan, though sound, is running out of steam. Instead of being well on the way to protecting the nation's civilian population by vaccinating up to
Kenneth D. Bloem, William J. Bicknell
core  

Effect of exposure to Neospora caninum, Salmonella, and Leptospira interrogans serovar Hardjo on the economic performance of Irish dairy herds [PDF]

open access: yes, 2015
peer-reviewedThe objective of the current study was to quantify the effects of exposure to Salmonella, Neospora caninum, and Leptospira interrogans serovar Hardjo (L.
O'Doherty, Eugene   +3 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A benefit-cost analysis quantifying the broader socioeconomic value of adult respiratory vaccination programs in Japan

open access: yesExpert Review of Vaccines
Background Respiratory infections like pneumococcal disease (PD), respiratory syncytial virus (RSV), influenza (Flu), and COVID-19 significantly impact Japan’s aging population, imposing substantial health and economic burdens.
Claud Theakston   +9 more
doaj   +1 more source

Human Papillomavirus Infection: Prevention, Barriers to Vaccination, and the Need for Education [PDF]

open access: yes, 2016
While there is no known cure for HPV, prophylactic vaccination provides an effective method of primary prevention against HPV-related diseases. However, many females and males never receive the HPV vaccine as recommended.
Kessler, Theresa A
core   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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