Results 71 to 80 of about 4,221,129 (325)

Assessment of two essential elements of BVDV control on selected Flemish dairy and beef farms [PDF]

, 2013
Bovine viral diarrhea virus (BVDV) is one of the most important viruses to cause disease in cattle worldwide. The virus is endemically present in Belgium. Clinical diagnosis of BVDV infection is difficult.
Booth, Richard, De Vliegher, Sarne, Deprez, Piet, Dewulf, Jeroen, Laureyns, Jozef, Pfeiffer, Dirk, Sarrazin, Steven   +6 more
core  

Heterogeneity in the spread and control of infectious disease: consequences for the elimination of canine rabies [PDF]

, 2015
Understanding the factors influencing vaccination campaign effectiveness is vital in designing efficient disease elimination programmes. We investigated the importance of spatial heterogeneity in vaccination coverage and human-mediated dog movements for ...
Cleaveland, Sarah, Consunji, Ramona, Deray, Raffy, Ferguson, Elaine, Friar, John, Hampson, Katie, Haydon, Daniel T., Jimenez, Joji, Pancipane, Marlon, Townsend, Sunny E.   +9 more
core   +2 more sources

Adult vaccination as part of a healthy lifestyle: moving from medical intervention to health promotion

Annals medicus, 2019
As the global population ages, there is concern about the effect of an increased proportion of older individuals on the economic sustainability of healthcare systems and the social effects of an older society.
T. M. Doherty, G. Del Giudice, S. Maggi
semanticscholar   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Drivers of COVID-19 Vaccination among Eligible Adults in Abuja, Nigeria: A Mixed-Methods Study Using the WHO Behavioral and Social Drivers of Vaccination Framework

Vaccines
Despite the availability of COVID-19 vaccines, Nigeria still faces significant COVID-19 vaccine hesitancy, with only 60.7% of the eligible population fully vaccinated as of 20 March 2023.
Chizoba B. Wonodi, Ikechukwu A. Okpe, Pius U. Angioha, Affiong S. Ebong, Janet B. Adegbola, Abdulrasheed A. Abdulraheem, Nwamaka Ezeanya, Adewumi A. Adetola, Oluwatosin I. Arogundade, Goodness I. Hadley, Joseph A. Olisa   +10 more
doaj   +1 more source

The prevalence of occult hepatitis B virus (hbv) infection in a large multi-ethnic haemodialysis cohort. [PDF]

, 2015
Haemodialysis patients are at increased risk of exposure to blood borne viruses. To reduce transmission in the UK, all haemodialysis patients are regularly screened, and if susceptible to Hepatitis B virus (HBV) infection ...
Cross, J, Davenport, A, Haque, T, Labbett, W, O'Riordan, A, Patel, M, Sowole, L   +6 more
core   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Rectal Microbiome Composition Correlates with Humoral Immunity to HIV-1 in Vaccinated Rhesus Macaques. [PDF]

, 2019
The microbiome is an integral and dynamic component of the host and is emerging as a critical determinant of immune responses; however, its influence on vaccine immunogenicity is largely not well understood.
Dinasarapu, Ashok R, Durbin-Johnson, Blythe P, Elizaldi, Sonny R, Iyer, Smita S, Kozlowski, Pamela A, Raeman, Reben, Rolston, Matthew, Settles, Matthew, Verma, Anil, Walter, Korey A   +9 more
core   +1 more source

The age-specific burden and household and school-based predictors of child and adolescent tuberculosis infection in rural Uganda. [PDF]

, 2020
BackgroundThe age-specific epidemiology of child and adolescent tuberculosis (TB) is poorly understood, especially in rural areas of East Africa. We sought to characterize the age-specific prevalence and predictors of TB infection among children and ...
Atukunda, Mucunguzi, Balzer, Laura B, Chamie, Gabriel, Charlebois, Edwin D, Clark, Tamara D, Havlir, Diane V, Kamya, Moses R, Kironde, Joel, Kwarisiima, Dalsone, Marquez, Carina, Mwangwa, Florence, Petersen, Maya, Ruel, Theodore D, Ssemmondo, Emmanuel, Tram, Khai Hoan   +14 more
core   +2 more sources