Results 71 to 80 of about 1,914,795 (248)

Drivers of COVID-19 Vaccination among Eligible Adults in Abuja, Nigeria: A Mixed-Methods Study Using the WHO Behavioral and Social Drivers of Vaccination Framework

Vaccines
Despite the availability of COVID-19 vaccines, Nigeria still faces significant COVID-19 vaccine hesitancy, with only 60.7% of the eligible population fully vaccinated as of 20 March 2023.
Chizoba B. Wonodi, Ikechukwu A. Okpe, Pius U. Angioha, Affiong S. Ebong, Janet B. Adegbola, Abdulrasheed A. Abdulraheem, Nwamaka Ezeanya, Adewumi A. Adetola, Oluwatosin I. Arogundade, Goodness I. Hadley, Joseph A. Olisa   +10 more
doaj   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Vaccination for Older Adults in India: Position Statement of the Indian Academy of Geriatrics

Journal of the Indian Academy of Geriatrics
India’s rapidly aging population faces a dual burden of noncommunicable and infectious diseases, with older adults being particularly vulnerable due to immunosenescence.
Sunny Singhal, Gevesh Chand Dewangan, Pramod Kumar Mehta, Surekha Viggeswarpu, Aparajit Ballav Dey, Venugopalan Gunasekaran   +5 more
doaj   +1 more source

ECONOMIC AND BEHAVIORAL FACTORS IN AN INDIVIDUALfS DECISION TO TAKE THE INFLUENZA VACCINATION IN JAPAN [PDF]

In this paper, we investigate what people in Japan consider when deciding to take the influenza vaccination. We develop an economic model to explain the mechanism by which people decide to take the influenza vaccination.
Yoshiro Tsusui, Uri Benzion, Shosh Shahrabani   +2 more
core  

Improving community coverage of oral cholera mass vaccination campaigns: lessons learned in Zanzibar [PDF]

, 2012
BACKGROUND: Recent research in two cholera-endemic communities of Zanzibar has shown that a majority (?94%) of the adult population was willing to receive free oral cholera vaccines (OCVs). Since OCV uptake in the 2009 campaign reached only ?50% in these
Claire-Lise Chaignat, Weiss Mitchell G., Schaetti, C., Weiss, M. G., Khatib, A. M., Ahmed M. Khatib (130136), Said M. Ali, Mitchell G Weiss, Hutubessy Raymond, Schaetti Christian, Ahmed M Khatib, Claire-Lise Chaignat (127845), Raymond Hutubessy (130149), Ali, S. M., Khatib Ahmed M., Mitchell G. Weiss, Mitchell G. Weiss (130129), Ahmed M. Khatib, Chaignat Claire-Lise, Ali Said M., Hutubessy, R., Christian Schaetti (130127), Chaignat, C. L., Raymond Hutubessy, Christian Schaetti, Said M Ali, Said M. Ali (130132)   +26 more
core   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

A benefit-cost analysis quantifying the broader socioeconomic value of adult respiratory vaccination programs in Japan

Expert Review of Vaccines
Background Respiratory infections like pneumococcal disease (PD), respiratory syncytial virus (RSV), influenza (Flu), and COVID-19 significantly impact Japan’s aging population, imposing substantial health and economic burdens.
Claud Theakston, Matthew Napier, Simon Brassel, Kazumasa Kamei, Shuhei Ito, Jeffrey Vietri, Diana Mendes, Jingyan Yang, Tianyan Hu, Lotte Steuten   +9 more
doaj   +1 more source

Surveillance of Vaccination Coverage Among Adult Populations--United States, 2014 [PDF]

Problem/Condition: Overall, the prevalence of illness attributable to vaccine-preventable Diseases is greater among adults than among children. Adults are recommended to receive vaccinations based on their age, underlying medical conditions, lifestyle ...

core