Results 131 to 140 of about 6,150,027 (314)

Social Care and Young Adults with Neuromuscular Conditions Diagnosed in Childhood: A Co-Produced Scoping Review

Journal of Long-Term Care
Context: The social care needs of young adults with neuromuscular conditions (NMCs) are poorly evidenced. To address the paucity in research, it is first necessary to consolidate current understanding of social care and its presence/absence in the lives
George Peat, Suzanne Glover, Caterina Radu, Steven Jones, Grace Binney, James Parkin, Kirsty Liddiard, Lorna Katherine Fraser, David Abbott   +8 more
doaj   +1 more source

Transportation for an Aging Population: Promoting Mobility and Equity for Low-Income Seniors [PDF]

, 2018
This study explores the travel patterns, needs, and mobility problems faced by diverse low-income, inner-city older adults in Los Angeles in order to identify solutions to their mobility challenges.
Brozen, Madeline, Levy-Storms, Lené, Loukaitou-Sideris, Anastasia, Wachs, Martin   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Guidelines for library service for young adults

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2001
Directrius per a la planificació i avaluació de serveis adreçats a adolescents en biblioteques ...
IFLA. Section of Library for Children and Young Adults
doaj  

The role of LH in follicle development: from physiology to new clinical implications

Reproductive Biology and Endocrinology
The process of follicle development is closely regulated by two pituitary gonadotropins: follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Maria Longo, Francesca Liuzzi, Serena De Carlini, Antonio La Marca   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Evaluating tumor chemosensitivity: a head-to-head comparison of the prognostic value of KELIM (modeled CA125 elimination rate constant K) and RECIST 1.1 (radiological response valuation criteria in solid tumors) in ovarian cancer

Archives of Gynecology and Obstetrics
Purpose The aim of the study was to analyze KELIM (modeled CA125 ELIMination rate constant K) and RECIST 1.1. (radiological response valuation criteria in solid tumors) as indicators of tumor chemosensitivity and their role in predicting patient ...
Kaja Michalczyk, Agata Mokrzycka, Marianna Rudzińska, Marcin Misiek, Anita Chudecka-Głaz   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Medicaid and Community Health Centers: The Relationship Between Coverage for Adults and Primary Care Capacity in Medically Underserved Communities [PDF]

, 2012
Compares the strength of health centers in states with expanded Medicaid coverage for adults and those in states with limited Medicaid coverage for adults, in terms of number of sites, patients, and staff; revenue; and proportion of revenue from ...

core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source