Results 121 to 130 of about 3,902,799 (310)

Surgery of the Aortic Valve Using a Minimally Invasive Approach

open access: yesУкраїнський журнал серцево-судинної хірургії
Aim. The aim of this study is to present and analyze the technique of isolated aortic valve replacement (AVR) or repair via a minimally invasive approach – right anterior thoracotomy in the second intercostal space. Materials and Methods.
Oleksandr D. Babliak   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

The role of LH in follicle development: from physiology to new clinical implications

open access: yesReproductive Biology and Endocrinology
The process of follicle development is closely regulated by two pituitary gonadotropins: follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Maria Longo   +3 more
doaj   +1 more source

Pediatric Cancers and Brain Tumors in Adolescents and Young Adults

open access: yes, 2016
Embryonal tumors classically occur in young children, some principally within the first year of life. Prospective national and international clinical trials during recent decades have brought about progressive improvements in survival, and associated ...
Dominique Valteau-Couanet   +4 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Evaluating tumor chemosensitivity: a head-to-head comparison of the prognostic value of KELIM (modeled CA125 elimination rate constant K) and RECIST 1.1 (radiological response valuation criteria in solid tumors) in ovarian cancer

open access: yesArchives of Gynecology and Obstetrics
Purpose The aim of the study was to analyze KELIM (modeled CA125 ELIMination rate constant K) and RECIST 1.1. (radiological response valuation criteria in solid tumors) as indicators of tumor chemosensitivity and their role in predicting patient ...
Kaja Michalczyk   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The burden of extra uterine growth restriction on postnatal growth in very low birth weight preterm newborns

open access: yesBMC Pediatrics
Background Extra-uterine growth restriction (EUGR) is a condition caused by the failure of very preterm infants to reach their potential growth during the NICU hospital stay. Despite improvements in nutritional supports, their growth pattern is still far
Laura Lucaccioni   +11 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Body position to optimize mechanics in ARDS: to which degree does the angle matter?

open access: yesIntensive Care Medicine Experimental, 2023
Jantine Wisse, Annemijn H. Jonkman
doaj   +1 more source

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