Results 141 to 150 of about 3,775,410 (310)

Lack of Oral Health Care for Adults in Harlem: A Hidden Crisis

open access: yes, 2002
OBJECTIVES: Profound and growing disparities exist in oral health among certain US populations. We sought here to determine the prevalence of oral health complaints among Harlem adults by measures of social class, as well as their access to oral health ...
Trinh, Chau   +8 more
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Elderly Adults' Preferences for Life-Sustaining Treatments: The Role of Impairment, Prognosis, and Pain

open access: yes, 1999
Elderly adults' preferences for life-sustaining treatment are known to vary by type of medical condition and treatment. Less is known about how treatment preferences vary based on underlying health dimensions, such as the nature of the impairment ...
Ditto, Peter H.   +5 more
core  

ITRS family and child outcomes [PDF]

open access: yes, 2010
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on Oct.

core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Adults' resistance to learn in school versus adults' competences in work : the case of mathematics

open access: yes, 2006
In adult education, resistance to learning is a well known phenomenon. There is an apparent contradiction between many adults' problematical relationships with mathematics in formal settings and their noteworthy "mathematics-containing" competences in ...
Evans, Jeff, Wedege, Tine,
core  

Phase-specific postural adjustments in children and adults during a challenging balance task

open access: yes
Introduction: Anticipatory postural adjustments (APAs) stabilize the body before voluntary movement. Although present early in life, their refinement continues into adolescence, especially during complex balance tasks.
Abdollahipour, Reza   +3 more
core   +1 more source

Older adults' comprehension of speech as interactive domestic alarm system output: A field study [PDF]

open access: yes, 2003
Please contact the publisher for further reprinting or re-use.A rapidly ageing population has led to the development of Interactive Domestic Alarm Systems (IDASs) to assist older adults with independent living.
Lines, L, Hone, KS
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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