Results 151 to 160 of about 10,055,911 (359)

Frailty in older adults: evidence for a phenotype.

The journals of gerontology. Series A, Biological sciences and medical sciences, 2001
Linda P. Fried, C. Tangen, J. Walston, Anne B. Newman, Calvin Hirsch, J. Gottdiener, Teresa E. Seeman, Russell P. Tracy, W. Kop, Gregory Burke, M. McBurnie   +10 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia [PDF]

, 2010
Hiba El Hajj, Marwan El‐Sabban, Hideki Hasegawa, Ghazi Zaatari, Julien Ablain, Shahrazad Saab, Anne Janin, Rami Mahfouz, Rihab Nasr, Youmna Kfoury, Christophe Nicot, Olivier Hermine, William W. Hall, Hugues de Thé, Ali Bazarbachi   +14 more
openalex   +1 more source

Hepatic safety and tolerability of cipargamin (KAE609), in adult patients with Plasmodium falciparum malaria: a randomized, phase II, controlled, dose-escalation trial in sub-Saharan Africa [PDF]

, 2021
Gilles Ndayisaba, Adoke Yeka, Kwaku Poku Asante, Martin P. Grobusch, Etienne Karita, Henry Mugerwa, Stephen Asiimwe, Abraham Oduro, Bakary Fofana, Seydou Doumbia, Jay Prakash Jain, Sarita Barsainya, Gerd A. Kullak‐Ublick, Guoqin Su, E. Schmitt, Katalin Csermak, Preetam Gandhi, David Hughes   +17 more
openalex   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Knowledge and Awareness of Risk Factors for HIV Infection and about HIV Testing among Medical Students in Warsaw

Viruses
Background: The number of late diagnoses of HIV remains very high in Poland, leading to a high proportion of patients developing and dying of HIV-related diseases. The main reason for this is the very low utilization of HIV testing. Our analyses aimed to
Justyna Kowalska, Martyna Cholewik, Carlo Bieńkowski, Aleksandra Maciejczyk, Dominik Bursa, Agata Skrzat-Klapaczyńska   +5 more
doaj   +1 more source

The occurrence of sleep-disordered breathing among middle-aged adults.

New England Journal of Medicine, 1993
T. Young, M. Palta, J. Dempsey, J. Skatrud, S. Weber, S. Badr   +5 more
semanticscholar   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

The Lives of Young Adults Who Have Graduated from Residential Children\u27s Mental Health Programs (FULL REPORT) [PDF]

, 2015
This report presents the results of a research process in which 59 young adults who had received residential mental health treatment in the past were sorted into descriptive profiles based on the information they shared about their lives and personal ...
Cameron, Gary, Frensch, Karen
core   +1 more source

Long-Acting Intranasal Insulin Detemir Improves Cognition for Adults with Mild Cognitive Impairment or Early-Stage Alzheimer's Disease Dementia

, 2015
Amy Claxton, Laura D. Baker, Angela J. Hanson, Emily H. Trittschuh, Brenna Cholerton, A. Morgan, Maureen Callaghan, Matthew Arbuckle, Christian Behl, Suzanne Craft   +9 more
openalex   +2 more sources