Results 151 to 160 of about 9,751,042 (392)

TETANY IN THE ADULT [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1909
n ...
openaire   +3 more sources

Blind Adults in America: Their Lives and Challenges [PDF]

open access: yes, 2004
In an effort to learn more about Americans with disabilities, the Centers for Disease Control and Prevention (CDC) decided that the National Health Interview Survey (NHIS) would be used to gather information about men, women, and children with ...
Diana M. Zuckerman
core  

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

Dissertation: Examining and investigating home modifications and smart home technologies to reduce fall injury among older adults. [PDF]

open access: yes, 2019
Nearly one in six U.S. residents are over the age of 65. The proportion of older adults in the U.S. is anticipated to grow to 22.1% of the total population by 2050.
Kwan, Kevin Parker
core  

An Initiative to Educate and Support Young Adults Diagnosed with Hypertension [PDF]

open access: yes, 2020
An Initiative to Educate and Support Young Adults Diagnosed with Hypertension Page Tomlinson, BS, RN, DNPc Background: Hypertension is a common diagnosis in the US with significant long-term effects.
Tomlinson, Page
core   +1 more source

Archaeal protein containing domain of unknown function 2193 undergoes oligomeric reconfiguration upon iron–sulfur cluster binding

open access: yesFEBS Letters, EarlyView.
This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter   +8 more
wiley   +1 more source

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Social Care and Young Adults with Neuromuscular Conditions Diagnosed in Childhood: A Co-Produced Scoping Review

open access: yesJournal of Long-Term Care
Context: The social care needs of young adults with neuromuscular conditions (NMCs) are poorly evidenced. To address the paucity in research, it is first necessary to consolidate current understanding of social care and its presence/absence in the lives
George Peat   +8 more
doaj   +1 more source

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