Results 91 to 100 of about 137,565 (304)
Spiritual Care Advance Directive (SCAD)
International Journal of Integrated Care, 2017 Objectives:1. Integrate not only the compassionate care at end-of-life chapter, but also the spiritual history to a deeper understanding of the individual’s dignity and legacy.2. Intervene in a process of the individual’s spiritual needs and wishes along the life-limiting illness trajectory.Background: Families and professionals have recognized the ...
openaire +3 more sources
Should Aggregate Patient Preference Data Be Used to Make Decisions on Behalf of Unrepresented Patients? [PDF]
, 2019 Patient preference predictors aim to solve the moral problem of making treatment decisions on behalf of incapacitated patients. This commentary on a case of an unrepresented patient at the end of life considers 3 related problems of such ...
Sharadin, Nathaniel
core
Inapplicability of advance directives in a paternalistic setting: the case of a post-communist health system [PDF]
, 2011 The Albanian medical system and Albanian health legislation have adopted a paternalistic position with regard to individual decision making. This reflects the practices of a not-so-remote past when state-run facilities and a totalitarian philosophy of ...
Gentian Vyshka, Jera Kruja
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Advance Care Planning for Adults With CKD: A Systematic Integrative Review [PDF]
, 2014 Author version made avilable in accordance with the publisher's policy. © 2014, the National Kindney Foundation, inc. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-
Brennan, Frank +8 more
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Palliative Care, 2019 Background: A Rapid Response Team can respond to critically ill patients in hospital to prevent further deterioration and unexpected deaths. However, approximately one-third of reviews involve a patient approaching the end-of-life.
Wendy Pearse +5 more
doaj +1 more source
Information and Advance Care Directives for End-of-Life Residents with and without Dementia in Nursing Homes. [PDF]
Healthcare (Basel), 2023 Mota-Romero E +5 more
europepmc +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source