Results 121 to 130 of about 181,542 (334)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
From Advance Directives or Living Wills to Advance Care Planning
NURE Investigación, 2004 Since 2000 a great amount of legal norms about advance directives documents has been developed in Spain. In this topic the experience of countries as USA and Canada is much longer, starting in the 60´s.
Inés Maria Barrio Cantalejo +2 more
doaj
The Future of Health Care [PDF]
, 2013 Two leaders in Maryland\u27s health care profession - Gary L. Attman \u2779 and Dr. Jay Perman - discuss the implications of a graying population, the transformative impact of technology, the importance of advance directives, and ...
core
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
USING MAINTENANCE OF CERTIFICATION TO PROMOTE ADVANCE DIRECTIVE DISCUSSIONS IN PRIMARY CARE [PDF]
, 2017 Edmund H. Duthie +4 more
openalex +1 more source
, 1988 Material appearing below is thought to be of particular interest to Linacre Quarterly readers because of its moral, religious, or philosophic content. The medical literature constitutes the primary but not the sole source of such material.
Catholic Physicians\u27 Guild
core +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Stopping Eating and Drinking by Advance Directives: Choose Your Injustice [PDF]
, 2019 Peter Jaggard, James D. Wright
openalex +1 more source