Results 141 to 150 of about 1,191,211 (370)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Personal identity and advance directives [PDF]

, 1994
Treatment decisions for incompetent patients are frequently based on the patient\u27s prior expressed wishes when competent. The merit of this approach is that it is consistent with a respect for patient self-determination and extends the rights of the ...
Buller, Thomas Gilbert
core   +1 more source

BMA division disagrees with association's stance over advance directives [PDF]

, 1996
Ian Jessiman
openalex   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

FEBS Letters, EarlyView.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Awareness of Advance Planning for End of Life: A Qualitative Study of \u27Baby Boomers\u27 [PDF]

, 2005
This qualitative study examined factors that contribute to end of life decision-making regarding formulation of advance directives for individuals within the \u27baby boomer\u27 age range.
Morse, Elizabeth Lada
core  

Making Sense of Advance Directives (2nd ed) [PDF]

, 1997
Ann Sommerville
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Implementation of early will directives: facilities and difficulties experienced by palliative care teams

Revista Gaúcha de Enfermagem
Objective: To know the facilities and difficulties the palliative care team professionals experience in the implementation process of advance healthcare directives.
Aline Carniato Dalle Nogario, Edison Luiz Devos Barlem, Jamila Geri Tomaschewski-Barlem, Rosemary Silva da Silveira, Silvana Bastos Cogo, Deciane Pintanela de Carvalho   +5 more
doaj   +2 more sources

Japanese Patients' Preferences for Receiving Cancer Test Results While in the United States: Introducing an Advance Directive for Cancer Disclosure [PDF]

, 2000
Michael D. Fetters, Yuichiro Masuda
openalex   +1 more source