Results 251 to 260 of about 181,542 (334)

Advance directives as autonomy enhancers: reality or myth?

, 2015
Mónica Navarro-Michel
openalex   +2 more sources

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Attitudes of the Portuguese population towards advance directives: an online survey. [PDF]

BMC Med Ethics
Macedo JC, Castro L, Nunes R.
europepmc   +1 more source

Grace at the End of Life: Rethinking Ordinary and Extraordinary Means in a Global Context [PDF]

, 2019
Kelly, Conor M.
core   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Portuguese Advance Directives-a twist against futility? A cross sectional study. [PDF]

Sao Paulo Med J
Martins CS, Nunes R.
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Integration of Psychiatric Advance Directives Into the Patient-Accessible Electronic Health Record: Exploring the Promise and Limitations.

J Med Internet Res
Schwarz J, Meier-Diedrich E, Scholten M, Stephenson L, Torous J, Wurster F, Blease C.   +6 more
europepmc   +1 more source

Aligning goals with care: Advance directives in older adults with implantable cardioverter-defibrillators. [PDF]

Pacing Clin Electrophysiol
Backman WD, DiCaro MV, Zuo X, Peralta A, Orkaby AR.   +4 more
europepmc   +1 more source