Results 111 to 120 of about 9,005,057 (309)

ACC 411 A: Advanced Accounting

, 2011
CODE: ACC 411 A UNIT: ADVANCED ACCOUNTINGDaystar ...
Daystar University
core  

Pregnancy and advanced maternal age [PDF]

, 2015
Advanced maternal age has been a common occurrence within the last decade. Today, women are much more active outside of the home and childbearing has been postponed as careers and finances have become the main focus of younger adult women.
Carey, Dominyse
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Application effect of negative pressure venous indwelling needle drip puncture in venipuncture of elderly patients

Huli yanjiu
ObjectiveTo study the clinical effect of negative pressure venous indwelling needle drip puncture in venipuncture of elderly patients.MethodsA total of 200 elderly patients hospitalized in our hospital from April 2021 to April 2023 were selected as ...
PENG Lili, YAN Yafeng
doaj  

Hospital visits in advanced age

, 2015
Presents key findings about the hospital visits of people in advanced age, including hospitalisations, re-admissions, visits to hospital-based doctors and after-hours medical clinics.
LiLACS NZ
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Liver resection in advanced age

, 1995
Summary. The authors report the good operative results of liver resection in a group of well selected elderly patients.
Giovannini, Ivo, Giuliante, Felice, Chiarla, Carlo, Cavicchioni, Camillo, Vellone, Maria, Nuzzo, Gennaro, Boldrini, Giuseppe   +6 more
core  

Advanced maternal age

, 2011
Delayed childbearing is a growing trend in developed countries. Between 1989 and 2009, the number of live births to UK women over 40 almost trebled. This accelerating demographic shift is of major clinical and public health concern, because advanced ...
Lavender, Tina, Mills, Tracey A., Tina Lavender, Tracey A. Mills   +3 more
core   +1 more source