Results 121 to 130 of about 9,005,057 (309)
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Revista Cubana de Hematología, Inmunología y Hemoterapia, 2006 La drepanocitosis incluye un grupo heterogéneo de procesos patológicos, tanto desde el punto de vista genético como clínico. Con el advenimiento de nuevas modalidades terapéuticas, la expectativa de vida para estos pacientes se ha elevado.
Rafael Losada Buchillón +5 more
doaj
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Challenges Associated with Advanced Maternal Age
, 2017 Background: Advanced maternal age is a growing social phenomenon. The proportion of first births to women ages 35 years and over in the United States have increased. Women are prolonging childbearing to accommodate their careers.
Patel, Krupa
core
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Male biological clock: a critical analysis of advanced paternal age
, 2015 Extensive research defines the impact of advanced maternal age on couples' fecundity and reproductive outcomes, but significantly less research has been focused on understanding the impact of advanced paternal age.
Lamb, Dolores J +3 more
core +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Retrospective Analysis of Advanced Maternal Age Pregnancies
, 2011 OBJECTIVE: To evaluate maternal and fetal outcome in pregnancies of women aged 35 and more. STUDY DESIGN: In this retrospective analysis of advanced maternal age pregnancies a total of 237 patient records were evaluated.
Aslı Göker Tamay +4 more
core
Pregnancy outcomes in women of very advanced maternal age
, 2005 Objective: To assess outcomes for pregnancies progressing beyond 20 weeks' gestation in women of very advanced maternal ...
Callaway, Leonie K. +2 more
core +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source