Cancer Clinical Trials Optimization and Pharmacogenomics [PDF]
, 2012 A critical overview of recent clinical trials in cancer is presented focused on signaling pathways blockers or inhibitors with a view to developing successful clinical trials employing personalized cancer therapies.
I. C. Baianu
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Association between diverticulosis and colonic neoplastic lesions in individuals with a positive faecal immunochemical test [PDF]
, 2017 Background The association between diverticulosis and colonic neoplastic lesions has been suggested, but data in literature are conflicting. This study aimed to investigate such a relationship in patients participating in a colorectal cancer screening ...
Boggi, R. +7 more
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Palliative Medicine Reports, 2021 Background: Understanding ethnic disparities in end-of-life care (EOLC) intensity is central to improving outcomes for diverse populations. Although Chinese Americans represent one of the fastest growing ethnic groups in the United States, little is ...
Emma Ernst +3 more
doaj +1 more source
Enhanced anticancer activity of a combination of docetaxel and Aneustat (OMN54) in a patient-derived, advanced prostate cancer tissue xenograft model. [PDF]
, 2013 The current first-line treatment for advanced metastatic prostate cancer, i.e. docetaxel-based therapy, is only marginally effective. The aim of the present study was to determine whether such therapy can be improved by combining docetaxel with Aneustat (
Collins, Colin C +9 more
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RRx-001 in Refractory Small-Cell Lung Carcinoma: A Case Report of a Partial Response after a Third Reintroduction of Platinum Doublets. [PDF]
, 2016 RRx-001 is a pan-active, systemically nontoxic epigenetic inhibitor under investigation in advanced non-small cell lung cancer, small-cell lung cancer and high-grade neuroendocrine tumors in a Phase II clinical trial entitled TRIPLE THREAT (NCT02489903),
Brzezniak, Christina +12 more
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Rapid, ultra low coverage copy number profiling of cell-free DNA as a precision oncology screening strategy. [PDF]
, 2017 Current cell-free DNA (cfDNA) next generation sequencing (NGS) precision oncology workflows are typically limited to targeted and/or disease-specific applications.
Alva, Ajjai S +31 more
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The Present State of Existential Interventions Within Palliative Care
Frontiers in Psychiatry, 2022 Existential psychotherapy is rooted in the European tradition of existential philosophy. Existential philosophers include Husserl and Heidegger, who were German, and Camus, Sartre, de Beauvoir, and Merleau-Ponty, who were French.
Takeshi Terao, Moriaki Satoh
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Advancements in Cancer Immunotherapies
Vaccines, 2022 Recent work has suggested involvement of the immune system in biological therapies specifically targeting tumor microenvironment. Substantial advancement in the treatment of malignant tumors utilizing immune cells, most importantly T cells that play a key role in cell-mediated immunity, have led to success in clinical trials.
Ruchi Roy, Sunil Singh, Sweta Misra
openaire +3 more sources
Conversion of a gastric band into an intraperitoneal port in a patient with optimally debulked stage 3C serous ovarian carcinoma [PDF]
, 2015 Intraperitoneal (IP) chemotherapy in women with optimally debulked stage 3 ovarian cancer improves overall survival and progression-free survival, and its use has been encouraged in the adjuvant treatment of appropriately selected patients (Armstrong et ...
Cohen, P, Tan, J, Tan, J, Tucker, P
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Quality of life in patients with advanced cancer according to place of care in a referral hospital.
Revista de la Facultad de Medicina Humana, 2021 The quality of life perceived by patients with advanced cancer from a tertiary hospital is compared according to home care versus hospital care. Observational, cross-sectional study, included patients older than 18 years with cancer with multiple ...
Jose Amado Tineo +5 more
doaj +1 more source