Results 71 to 80 of about 4,649,569 (285)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Oscillation of Second-Order Noncanonical Advanced Type Neutral Differential Equations

Mathematics
This paper establishes new oscillation criteria for a specific class of second-order nonlinear noncanonical neutral differential equations that incorporate an advanced neutral argument. Rather than analyzing the equation in its initial noncanonical state,
Muniyappan Vijayakumar, Gopal Shankar, Ilhem Kadri, Manal Y. A. Juma, Nidal E. Taha   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Multivariable Calculus, Linear Algebra, and Differential Equations

, 1986
Multivariable Calculus, Linear Algebra, and Differential Equations, Second Edition contains a comprehensive coverage of the study of advanced calculus, linear algebra, and differential equations for sophomore college students.The text includes a large ...
Grossman, Stanley I.
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Riccati differential equations /

, 1972
Includes bibliographical references and index.Front Cover; Riccati Differential Equations; Copyright Page; Contents; Preface; Chapter One. Scalar Riccati Differential Equations; Chapter Two.
Reid, William T.(William Thomas),1907 October 4-1977.
core  

Qualitative theory of differential equations

, 2022
Az 1988. aug. 22-26. között Szegeden, a József Attila Tudományegyetem Természettudományi Karának Bolyai Intézete által rendezett 3. Colloquium on the Qualitative Theory of Differential Equations előadásaied. by B.

core  

Solutions of an advance-delay differential equation and their asymptotic behaviour

Archivum Mathematicum, 2023
The paper investigate the existence of the global solution for the following differential equation with both the delay and advanced arguments \[ \dot{y}(t)=-\left(a_0+\frac{a_1}{t}\right)y(t-\tau)+\left(b_0+\frac{b_1}{t}\right)y(t+\sigma).\tag{1.2} \] The approximated solution is found in the form \[ y_{as}(t)=e^{\lambda t}t^{-r}\left(1-\frac{A}{t ...
openaire   +2 more sources

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source