Results 61 to 70 of about 288,723 (312)

The ErbB2 receptor in gastric cancer. the quick-change artist [PDF]

, 2015
The ErbB family of receptors is providing the oncogenic signals necessary to cells to become transformed. In gastric cancer (GC) the ErbB2 (HER2) expression is associated with a poor prognosis, but addition of ErbB-targeted therapeutics to chemotherapy ...
Alimandi, Maurizio, D'Aloia, MARIA MICHELA, Malaguti, Paola   +2 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

A complete response to S-1 plus cis-diamminedichloroplatinum in advanced-stage esophageal and gastric adenocarcinoma: a case report

World Journal of Surgical Oncology, 2012
Background Complete remission from advanced-stage synchronous double primary (SDP) esophageal and gastric adenocarcinoma by chemotherapy alone is rare.
Matsuno Yoritaka, Kochi Mitsugu, Fujii Masashi, Kanamori Noriaki, Kaiga Teruo, Mihara Yoshiaki, Funada Tomoya, Miyazaki Teruyuki, Takayama Tadatoshi   +8 more
doaj   +1 more source

Endoscopic and clinical evaluation of treatment and prognosis of Cronkhite-Canada syndrome: a Japanese nationwide survey. [PDF]

, 2016
BackgroundFirst reported in 1955, Cronkhite-Canada syndrome (CCS), a rare syndrome characterized by ectodermal abnormalities and inflammatory changes of the gastrointestinal tract mucosa, has been associated with a poor prognosis and life-threatening ...
Hibi, Toshifumi, Hirata, Ichiro, Hokari, Ryota, Kaunitz, Jonathan D, Komoto, Shunsuke, Miura, Soichiro, Tanaka, Masanori, Tomita, Kengo, Watanabe, Chikako   +8 more
core   +1 more source

Lnc RNA HOTAIR functions as a competing endogenous RNA to regulate HER2 expression by sponging miR-331-3p in gastric cancer [PDF]

, 2014
BACKGROUND: Accumulating evidence indicates that the long non-coding RNA HOTAIR plays a critical role in cancer progression and metastasis. However, the overall biological role and clinical significance of HOTAIR in gastric carcinogenesis remains largely
Dan-dan Yin, Er-bao Zhang, Feng-qi Nie, Jin-hai Li, Kai-hua Lu, Ke-ming Wang, Ming Sun, Rong Kong, Rui Xia, Wei De, Xiang-hua Liu, Ying-bin Ge, Zhao-xia Wang   +12 more
core   +4 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Combination of cadonilimab (PD-1/CTLA-4 bispecific antibody) and apatinib as salvage therapy achieves partial response in MSI-H advanced gastric cancer: a case report

Frontiers in Immunology
Microsatellite instability-high (MSI-H) gastric cancer (GC) is recognized as a unique subtype of gastric cancer. While patients with advanced MSI-H gastric cancer may respond favorably to a combination of immune checkpoint inhibitors and chemotherapy in ...
Jiayu Zhao, Xiaoxiao Li, Xiaoyuan Sun, Ruoxi Xiao, Juan Xue, Kexin Sui, Zimin Liu   +6 more
doaj   +1 more source

THE CHOICE OF SURGICAL TACTICS BASED ON THE RESULTS OF PIGMENTED LIMPHOGRAPHY FOR PATIENTS WITH LOCALLY ADVANCED PROXIMAL GASTRIC CANCER

Сибирский онкологический журнал, 2017
Introduction. The lack of low-cost and available methods for the diagnosis of lymph node metastasis from gastric cancer and the standards of surgery for proximal gastric cancer is a hot topic for research.
M. O. Maksimov, S. A. Tuzikov, G. N. Strizhakov, E. O. Rodionov, S. V. Miller   +4 more
doaj   +1 more source

Simultaneous colonic metastasis of advanced gastric cancer: a case report

Surgical Case Reports, 2023
Background Although distant metastasis in gastric cancer can be present at the time of the initial diagnosis, colonic metastasis is extremely rare. This report describes a case of simultaneous colonic metastasis of advanced gastric cancer.
Takafumi Shima, Asami Arita, Satoshi Sugimoto, Shoichi Takayama, Nao Kawaguchi, Yoshiro Imai, Tomohiro Kitahara, Tamaki Maeda, Junji Okuda   +8 more
doaj   +1 more source

Update on biomarkers in development of anti-angiogenic drugs in gastric cancer [PDF]

, 2016
The treatment of advanced gastric cancer remains challenging as the outcomes achieved with surgery alone or adjuvant or neoadjuvant chemotherapy and radiotherapy are poor. New treatment strategies are emerging and being tested in advanced gastric cancer.
Cai, Jun, Jia, S.
core   +1 more source