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The role of advanced glycation end products in retinal ageing and disease
Biochimica et Biophysica Acta (BBA) - General Subjects, 2009The retina is exposed to a lifetime of potentially damaging environmental and physiological factors that make the component cells exquisitely sensitive to age-related processes. Retinal ageing is complex and a raft of abnormalities can accumulate in all layers of the retina.
Glenn, Josephine V., Stitt, Alan W.
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Hepatic clearance of advanced glycation end products (AGEs)—myth or truth? [PDF]
The liver sequesters a number of circulating macromolecular soluble and particular waste products. This blood clearance function is carried out by the cells that line the sinusoidal wall: (i) the resident liver macrophages, or the Kupffer cells (KC), and (ii) the liver sinusoidal endothelial cells (LSEC).
Dmitri Svistounov, Bård Smedsrød
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Advanced Glycation End Products (AGEs) in Diabetic Complications
2017Hyperglycemic condition in diabetes accelerates formation of advanced glycation end products (AGEs) that are formed as a result of series of reaction between reducing sugars and proteins. Accumulation of AGEs has been implicated in development of insulin resistance as well as in the pathogenesis of diabetic complications.
Shweta Bhat +3 more
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Bone Aging by Advanced Glycation End Products
Journal of Dental Research, 2015The quality and quantity of mandibular bone are essential prerequisites for osseointegrated implants. Only the Hounsfield unit on preoperative computed tomography is currently used as a clinical index. Nevertheless, a considerable mismatch occurs between bone quality and the Hounsfield unit.
K Ganeko +7 more
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Phytochemicals Against Advanced Glycation End Products (AGEs) and the Receptor System
Current Pharmaceutical Design, 2017Reducing sugars can react non-enzymatically with amino groups of proteins and lipids to form irreversibly cross-linked macroprotein derivatives called as advanced glycation end products (AGEs). Cross-linking modification of extracellular matrix proteins by AGEs deteriorate their tertiary structural integrity and function, contributing to aging-related ...
Takanori Matsui +6 more
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Smooth Muscle Cell Pathophysiology and Advanced Glycation End Products (AGEs)
Current Drug Targets, 2010Accelerated atherosclerosis is the leading cause of coronary heart disease and stroke, which could account for high mortality rates in patients with diabetes. Although several hyperglycemia-elicited metabolic and hemodynamic derangements have been implicated in the pathogenesis of cardiovascular disease (CVD) in diabetes, the process of formation and ...
Takanori Matsui, Sho-ichi Yamagishi
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Circulating tumor DNA in advanced solid tumors: Clinical relevance and future directions
Ca-A Cancer Journal for Clinicians, 2021Michael L Cheng +2 more
exaly
Advanced glycation end-products (AGEs) in foods and their detecting techniques and methods: A review
Trends in Food Science & Technology, 2018Qingyi Wei, Ting Liu, Da‐Wen Sun
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