Results 81 to 90 of about 4,843,849 (291)

Feasibility of continuous high-resolution bioreactance monitoring during cesarean delivery under spinal anesthesia

open access: yesFrontiers in Medicine
PurposeThis study is the first to apply bioreactance-based hemodynamic monitoring with a 4-s interval during cesarean delivery under spinal anesthesia.
Christine Gaik   +8 more
doaj   +1 more source

Functional hemodynamic monitoring.

open access: yes, 2005
Hemodynamic monitoring is a central component of intensive care. Patterns of hemodynamic variables often suggest cardiogenic, hypovolemic, obstructive, or distributive (septic) etiologies to cardiovascular insufficiency, thus defining the specific ...
Payen, Didier, Pinsky, Michael R
core   +1 more source

Optimizing Cancer Vaccinations Using a Physiologically‐Based Pharmacokinetic/Pharmacodynamic (PBPK/PD) Model

open access: yesAdvanced Science, EarlyView.
Where and when should a cancer vaccine be administered? A whole‐body PBPK model demonstrates that systemic immune transport critically determines vaccination efficacy. By simulating how organ‐specific immune interactions influence treatment response, the study provides a quantitative framework for optimizing cancer vaccination strategies.
Mohammad R. Nikmaneshi   +2 more
wiley   +1 more source

Intraoperative hemodynamic monitoring during organ transplantation: what is new?

open access: yes, 2009
Purpose of review To highlight the recent developments in hemodynamic monitoring during liver and lung transplantation. Recent findings Even though a consensus on intraoperative hemodynamic monitoring is still lacking, the most frequently monitoring tool
DELLA ROCCA, Giorgio   +5 more
core   +1 more source

Non-invasive hemodynamic monitoring in trauma patients. [PDF]

open access: yes, 2015
BACKGROUND The assessment of hemodynamic status is a crucial task in the initial evaluation of trauma patients. However, blood pressure and heart rate are often misleading, as multiple variables may impact these conventional parameters.
Beat Schnüriger   +8 more
core   +2 more sources

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

open access: yesAdvanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng   +17 more
wiley   +1 more source

Perioperative Goal-Directed Therapy Using Invasive Uncalibrated Pulse Contour Analysis

open access: yesFrontiers in Medicine, 2018
“Perioperative goal-directed therapy” (PGDT) aims at an optimization of basic and advanced global hemodynamic variables to maintain adequate oxygen delivery to the end-organs.
Bernd Saugel, Daniel A. Reuter
doaj   +1 more source

Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

open access: yesAdvanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin   +13 more
wiley   +1 more source

Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies

open access: yesAdvanced Intelligent Systems, EarlyView.
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò   +7 more
wiley   +1 more source

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