Results 91 to 100 of about 323,704 (343)

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

open access: yesAdvanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen   +11 more
wiley   +1 more source

Impact of Advanced Maternal Age on Perinatal Outcomes

open access: yesGynecology Obstetrics & Reproductive Medicine, 2008
OBJECTIVES: To investigate the impact of advanced maternal age on perinatal outcomes. STUDY DESIGN: In this retrospective study, pregnancy records of 616 singletons were reviewed.
İlknur İnegöl Gümüş   +4 more
doaj  

Chromosome microarray analysis as first-line test in pregnancies with a priori low risk for detection of submicroscopic chromosomal abnormalities [PDF]

open access: yes, 2012
n this study, we aimed to explore the utility of chromosomal microarray analysis (CMA) in groups of pregnancies with a priori low risk for detection of submicroscopic chromosome abnormalities, usually not considered an indication for testing, in order to
A Breman   +54 more
core   +1 more source

Age and Maternal Mortality in Japan: Increased Maternal Mortality in Advanced Maternal Age

open access: yes, 2023
Abstract Objectives: This study aimed to clarify the relationship between maternal mortality and advanced maternal age in Japan and to provide useful information for future perinatal management. Methods: Maternal death rates by age group were investigated for all maternal deaths in Japan for an 11-year period, from 2010 to 2021. Maternal deaths
Hiroaki Tanaka   +11 more
openaire   +1 more source

Microglia Mitochondria Support Neuronal Maturation via Metabolic and Transcriptional Reprogramming in Human 3D In Vitro Brain Model

open access: yesAdvanced Science, EarlyView.
xx xx. ABSTRACT Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by disrupted neuronal circuit maturation. Emerging evidence implicates microglial function and mitochondrial regulation as contributors to ASD‐associated biology, yet the mechanisms linking these processes to neuronal development remain poorly defined ...
Sydney P. Sterben   +4 more
wiley   +1 more source

Retrospective Analysis of Advanced Maternal Age Pregnancies

open access: yesGynecology Obstetrics & Reproductive Medicine, 2011
OBJECTIVE: To evaluate maternal and fetal outcome in pregnancies of women aged 35 and more. STUDY DESIGN: In this retrospective analysis of advanced maternal age pregnancies a total of 237 patient records were evaluated.
Aslı Göker Tamay   +4 more
doaj  

Primiparity at an Advanced Age: Emerging Pattern Needing Courtesy to Achieve SDG Maternal Health Targets

open access: yesInternational Journal of Women's Health, 2023
Yadeta Dessie School of Public Health, College of Health and Medical Sciences, Haramaya University, Harar, EthiopiaCorrespondence: Yadeta Dessie, Email yad_de2005@yahoo.comAbstract: Primiparity at an advanced age, which means having a first birth at age ...
Dessie Y
doaj  

Factors Associated with Prenatal Folic Acid and Iron Supplementation Among 21,889 Pregnant women in Northern Tanzania: A Cross-Sectional Hospital-Based Study. [PDF]

open access: yes, 2012
Folate and iron deficiency during pregnancy are risk factors for anaemia, preterm delivery, and low birth weight, and may contribute to poor neonatal health and increased maternal mortality.
Daltveit, Anne Kjersti   +6 more
core   +4 more sources

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

open access: yesAdvanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat   +6 more
wiley   +1 more source

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