Results 71 to 80 of about 7,571,371 (245)

Paternal age in relation to offspring intelligence in the West of Scotland Twenty-07 prospective cohort study. [PDF]

, 2012
Background The adverse effects of advancing maternal age on offspring's health and development are well understood. Much less is known about the impact of paternal age.
Batty, G.D., Benzeval, Michaela, Michaela Benzeval, Deary, Ian J., Ian J Deary, G David Batty, Whitley, E, Benzeval, M, Der, G, Whitley Elise, Elise Whitley, Deary, Ian J, Whitley, E., Der, Geoff, Geoff Der, Deary Ian J., Der, G., Batty G. David, Batty, GD, Whitley, Elise, Benzeval, M., Benzeval Michaela, Batty, G David, Deary, IJ, Deary, I.J., Batty, G. David, Der Geoff   +26 more
core   +1 more source

Pregnancy Outcomes in Women of Advanced Age

Journal of Family and Reproductive Health, 2011
Objective: The aim of this study was to investigate prenatal and obstetrical outcome in mothers aged 40 years or older. Materials and methods: A prospective comparative study was conducted for the women aged 40 years and over who delivered at 20 week's ...
Mehrnaz Valadan, Fatemeh Tanha, Azam Sepahi   +2 more
doaj  

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

Advanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo, Ke Fang, Changjiang Zhao, Jiachao Xiong, Yuan Zhu, Mingyang Lu, He Yan, Zihan Li, Baojin Wu, Hua Jiang, Yufei Li   +10 more
wiley   +1 more source

The Effect of Maternal Multiple Micronutrient Supplementation on Cognition and Mood during Pregnancy and Postpartum in Indonesia: A Randomized Trial [PDF]

, 2012
Maternal caregiving capacity, which is affected in part by cognition and mood, is crucial for the health of mothers and infants. Few interventions aim to improve maternal and infant health through improving such capacity.
Shankar, Anuraj H., Muadz, Husni, Alcock, Katherine J., Prado, Elizabeth L., Ullman, Michael T.   +4 more
core   +4 more sources

Qualitative and Quantitative Fitness Consequences of Advanced Maternal Age [PDF]

, 2019
Parental age can affect offspring fitness across taxa and through various mechanisms. However, the effect(s) of advanced maternal age on offspring, particularly in insects, has not been comprehensively reviewed making it difficult to draw conclusions ...
Hallagan, Claudia Jean
core   +1 more source

Impact of Advanced Maternal Age on Perinatal Outcomes

Gynecology Obstetrics & Reproductive Medicine, 2008
OBJECTIVES: To investigate the impact of advanced maternal age on perinatal outcomes. STUDY DESIGN: In this retrospective study, pregnancy records of 616 singletons were reviewed.
İlknur İnegöl Gümüş, Zeynep Kamalak, Hilal Yuvacı, Candan İltemur Duvan, Nilgün Öztürk Turhan   +4 more
doaj  

The updated understanding of advanced maternal age

Fundamental Research
The rising rates of pregnancies associated with advanced maternal age (AMA) have created unique challenges for healthcare systems worldwide. The elevated risk of poor maternal outcomes among AMA pregnancies is only partially understood and hotly debated.
Xuan Ye, Philip N. Baker, Chao Tong
doaj   +1 more source

Optimized Cas9‐Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders

Advanced Science, EarlyView.
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee, Chanju Jung, Minjeong Kim, Narae Kim, Gue‐Ho Hwang, Soon‐Tae Lee, Kon Chu, Sang Kun Lee, Han‐Joon Kim, Jong‐Hee Chae, Sangsu Bae, Jangsup Moon   +11 more
wiley   +1 more source

Challenges Associated with Advanced Maternal Age

, 2017
Background: Advanced maternal age is a growing social phenomenon. The proportion of first births to women ages 35 years and over in the United States have increased. Women are prolonging childbearing to accommodate their careers.
Patel, Krupa
core   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source