Results 51 to 60 of about 7,571,371 (245)

First-Trimester Platelet Count as a Predictive Biomarker for Neonatal Birth Weight Among Pregnant Women at Advanced Maternal Age

Clinical and Applied Thrombosis/Hemostasis, 2020
The aim of this study was to investigate the association between first-trimester platelet count and neonatal birth weight in pregnant woman at advanced maternal age.
You-Fan Peng MD, PhD, Qiong Wei MD, PhD, Jin-Fang Sun MD, PhD, Ling Li MD, PhD   +3 more
doaj   +1 more source

Assessing the Sensitivity and the Clinical Impact of the 2023 American College of Rheumatology/EULAR Classification Criteria in Obstetric Antiphospholid Syndrome: Findings From a Multicenter Italian Cohort With a Long‐Term Follow‐Up

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli, Cecilia Nalli, Francesca Crisafulli, Carlo Garaffoni, Marcello Govoni, Giulia Voltarel, Alba C. Pozzi, Beatrice Maranini, Ettore Silvagni, Alessandra Bortoluzzi, Angela Tincani   +10 more
wiley   +1 more source

Risk of advanced colorectal neoplasia according to age and gender. [PDF]

, 2011
Colorectal cancer (CRC) is one of the leading causes of cancer related morbidity and death. Despite the fact that the mean age at diagnosis of CRC is lower in men, screening by colonoscopy or fecal occult blood test (FOBT) is initiated at same age in ...
Alexander Crispin, Burkhard Göke, Wagner, A., Crispin, Alexander, Göke, Burkhard, Frank T. Kolligs, Frank T Kolligs, Kolligs, Frank T., Andreas Wagner, Kolligs, F. T., Mansmann, Ulrich, Ulrich Mansmann, Wagner, Andreas, Axel Munte, Munte, A., Munte, Axel   +15 more
core   +2 more sources

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

Advanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi, Pere Català, Gabriel Größbacher, Paulina Nuñez Bernal, Olaf Nijssen, Sammy Florczak, Wilco Nijenhuis, Nuria Crusellas‐Villorbina, Bram Nijhoff, Paul Delrot, Jos Malda, Andreas Hierholzer, Martin Fussenegger, Lukas C. Kapitein, Riccardo Levato   +14 more
wiley   +1 more source

Impact of maternal age on obstetric and neonatal morbidity: a retrospective cohort study

BMC Pregnancy and Childbirth, 2021
Background Pregnancies in women over 35 years of age are becoming more frequent. The majority of studies point to an age of 35 as a provider of obstetric and neonatal complications.
Mélanie Vandekerckhove, Mélanie Guignard, Marie-Sophie Civadier, Alexandra Benachi, Jean Bouyer   +4 more
doaj   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

The impact of fertility changes on maternal mortality [PDF]

As less developed countries experience lower fertility, the age/parity distribution of pregnancies may shift. While these shifts may affect maternal mortality levels, their exact impact remains largely unknown. The aim of this thesis is to quantify the
Huang, Wei
core   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Advanced maternal age and pregnancy outcomes: a multicountry assessment.

, 2022
To assess the association between advanced maternal age (AMA) and adverse pregnancy outcomes. Secondary analysis of the facility-based, cross-sectional data of the WHO Multicountry Survey on Maternal and Newborn Health.
J P Souza (13312902), N Intarut (13313040), Josh Vogel (13077579), WHO Multicountry Survey on Maternal Newborn Health (13313292), R Mori (7805234), P Lumbiganon (13312911), A M Gülmezoglu (13312905), M Laopaiboon (13313043), T Ganchimeg (13312974)   +8 more
core  

Experimental and comparative analyses of maternal age and senescence [PDF]

, 2019
Senescence is often described as an age-related physiological deterioration accompanied with declining fertility and increasing mortality, and it is believed to be the result of declining forces of natural selection.
Ivimey-Cook, Edward Richard
core   +3 more sources