Results 91 to 100 of about 17,535 (200)

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde   +4 more
wiley   +1 more source

Advanced paternal age diversifies individual trajectories of vocalization patterns in neonatal mice. [PDF]

open access: yesiScience, 2022
Mai L   +9 more
europepmc   +1 more source

Association between Advanced Paternal Age and Low Birthweight in Thai Population

open access: yesThai Journal of Obstetrics and Gynaecology, 2012
Objectives: To determine the association between advanced paternal age and low birthweightMaterials and Methods: This was a case-control study including primigravida women, age ≥ 18 years old, who delivered at Siriraj Hospital during January ...
Pawan Limvorapitux   +2 more
doaj  

Paternal Contributions to Recurrent Pregnancy Loss: Mechanisms, Biomarkers, and Therapeutic Approaches

open access: yesMedicina
Background and Objectives: Recurrent pregnancy loss (RPL) affects numerous couples worldwide and has traditionally been attributed mainly to maternal factors.
Aris Kaltsas   +6 more
doaj   +1 more source

Structural Variation Sequencing of 26 Amniotic Fluid Samples With Partial Gene Duplications and Postnatal Follow‐Up of the Fetuses

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Objectives Partial gene duplications (PGDups) are a significant contributor to genetic disease. The precise genomic location and structure of PGDups are often unresolved using conventional methods, so prenatal diagnosis for PGDups is challenging, especially without ultrasound abnormalities.
Shengfang Qin   +10 more
wiley   +1 more source

The Diagnosis and Prenatal Management of Non‐RHD Alloimmunizations

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Red blood cell (RBC) alloimmunization remains a relevant cause of hemolytic disease of the fetus and newborn (HDFN). Although RhD immunization has significantly decreased since the implementation of systematic prophylaxis, it is still the main cause of alloimmunization in pregnancy.
Mar Bennasar, Antoni Borrell
wiley   +1 more source

Advanced Paternal Age and Its Impact on Reproductive and Offspring Health: Integrating Evidence from Clinical and Translational Studies

open access: yesFertility & Reproduction
Background: Advanced paternal age (APA) has emerged as a critical factor in reproductive health outcomes. Objective: To comprehensively review the effects of increasing paternal age on fertility parameters, embryo quality, and offspring well-being ...
Ameet Patki, Ritu Hinduja
doaj   +1 more source

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