Results 81 to 90 of about 17,535 (200)

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

Genetic sequencing of children with malrotation and midgut volvulus: A cross‐sectional study

JPGN Reports, EarlyView.
Abstract Objectives Intestinal malrotation with midgut volvulus can cause a particularly severe form of pediatric intestinal failure and is often a cause of ultra‐short bowel syndrome (SBS), with longer dependence on parenteral nutrition. While malrotation can be found in several genetic syndromes, most occurrences of this condition are not associated ...
Jonathan A. Salazar, Shira Rockowitz, Courtney E. French, Wanqing Shao, Daniel M. Elman, Alexandra N. Carey, Tom Jaksic, Piotr Sliz, Wen Hann Tan, Christopher P. Duggan   +9 more
wiley   +1 more source

Effect of paternal resveratrol intake on mitochondria and telomere length in mouse embryos and offspring

The Journal of Reproduction and Development
Advanced paternal age affects embryonic development and offspring phenotypes. We previously demonstrated that resveratrol prevents age-associated declines in the mitochondrial DNA copy number (mt-cn) and telomere length (TL ...
Noko TERAMOTO, Nanako KOBAYASHI, Kokoa MITSUI, Asuka KAMIO, Komei SHIRASUNA, Hisataka IWATA   +5 more
doaj   +1 more source

The Swedish Arctic Fox Project: 40 years of research in ecology and conservation

The Journal of Wildlife Management, EarlyView.
The 4 central research themes in The Swedish Arctic Fox Project and key deliverables for practical conservation achieved over 4 decades. Abstract The scientific community widely recognizes the value of long‐term studies, especially those with individual‐level resolution; however, maintaining a consecutive data series is associated with multiple ...
Anders Angerbjörn, Julie Bommerlund, Christopher A. Cockerill, Love Dalén, Bodil Elmhagen, Rasmus Erlandsson, Malin Hasselgren, Peter Hellström, Malin Larm, Karin Norén, Magnus Tannerfeldt, Johan Wallén   +11 more
wiley   +1 more source

Obstetrical and Perinatal Outcomes Are Not Associated with Advanced Paternal Age in IVF or ICSI Pregnancies with Autologous Oocytes. [PDF]

Biology (Basel), 2023
Navarro-Gomezlechon A, Gil Juliá M, Pacheco-Rendón RM, Hervás I, Mossetti L, Rivera-Egea R, Garrido N.   +6 more
europepmc   +1 more source

Genetic Etiologies of Dystonia with Anarthria/Aphonia

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Dystonia with anarthria and/or aphonia (DAnAp) represents a distinctive phenotype manifesting across lifespan. Frequently associated with genetic disorders, early recognition is critical for diagnosis and management. Objectives To provide practical recommendations for the clinical evaluation of patients with DAnAp, enhancing ...
Anika Ménétrey, Eriberto Rayco, Maziar Emamikhah Abarghouei, Susan H. Fox, Anthony E. Lang, George M. Ibrahim, Carolina Gorodetsky, Christos Ganos   +7 more
wiley   +1 more source

Hyperhomocysteinemia and Vitamin B Deficiency as Potential Aggravating Factors in Huntington's Disease: A Prospective Monocentric Study

Movement Disorders, EarlyView.
Abstract Background Although not confirmed, some studies have suggested that elevated homocysteine levels are common in patients with Huntington's disease (HD). Its clinical relevance remains unclear. Objectives We aimed to assess vitamin B and homocysteine levels in HD patients and explore the relationships among hyperhomocysteinemia, vitamin B ...
Salomé Puisieux, Elise Pourié, Céline Bonnet, Lucie Hopes, Solène Frismand, Myriam Bronner, Virginie Roth, Marion Wandzel, Natacha Sloboda, Laetitia Lambert, Abderrahim Oussalah, Amélia Julien, Irina Rotaru, Rosa‐Maria Guéant‐Rodriguez, Jean Louis Guéant, Carine Bossenmeyer‐Pourié, Mathilde Renaud   +16 more
wiley   +1 more source

Impact of Advanced Paternal Age on Fertility and Risks of Genetic Disorders in Offspring. [PDF]

Genes (Basel), 2023
Kaltsas A, Moustakli E, Zikopoulos A, Georgiou I, Dimitriadis F, Symeonidis EN, Markou E, Michaelidis TM, Tien DMB, Giannakis I, Ioannidou EM, Papatsoris A, Tsounapi P, Takenaka A, Sofikitis N, Zachariou A.   +15 more
europepmc   +1 more source

Convergence of Low‐Fertility Policies Beyond Policy Transfer: A Comparative Analysis of Korea and Hungary

Public Administration and Development, EarlyView.
ABSTRACT This study compares policy responses to persistent low fertility in Korea and Hungary, two countries facing similar demographic pressures but embedded in distinct institutional settings. It asks whether the diffusion of pronatalist policies has produced convergence in the design, implementation, and effects of fertility policy in these cases ...
Kilkon Ko, M. Jin Lee, Tamás Pesuth
wiley   +1 more source

Attitudes Toward Prenatal Interventions in the Fanconi Anemia Community

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective In‐utero cell and gene therapies may offer prenatal treatment options for inherited diseases. Preclinical data suggests in‐utero (IU) hematopoietic stem cell transplantation (HSCT) could prevent Fanconi anemia (FA) related bone marrow failure without genotoxic conditioning or immune suppression.
Tony Lum, Catherine Lee, Tippi MacKenzie, Billie Lianoglou, Agnieszka Czechowicz   +4 more
wiley   +1 more source