Results 61 to 70 of about 6,907,062 (191)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Effect of User Antenna Group Delay Variation Error on Advanced RAIM

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This study investigates the impact of antenna group delay variation (AGDV)-induced error on advanced receiver autonomous integrity monitoring. We model the AGDV error contribution not only as a measurement bias but also as a random process sigma term in ...
Eugene Bang, Mihaela-Simona Circiu, Stefano Caizzone, Markus Rippl, Omar Garcia Crespillo   +4 more
doaj   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

FEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli, Beatrice Lucia Bona, Francesca Baldelli Bombelli   +2 more
wiley   +1 more source

GNSS integrity monitoring for two satellite faults [PDF]

, 2009
To enable the use of multiple satellite navigation systems in aviation, Receiver Autonomous Integrity Monitoring will be required to detect the presence of multiple satellite failures.
Knight, N, Wang, J ; https://orcid.org/, Han, S, Rizos, C ; https://orcid.org/   +3 more
core   +1 more source

GBS‐MeDIP: A method for the simultaneous identification of genetic and epigenetic variants in tumors

FEBS Open Bio, EarlyView.
GBS‐MeDIP combines DNA sequencing with enrichment of methylated DNA to profile genetic and epigenetic variation in the same reduced genomic fraction. Applied to gastric cancer and parathyroid tumors, it identifies sequence variants, copy number changes, and differentially methylated regions together, helping distinguish true epigenetic changes from ...
Fábio Pértille, Shiva Rezaei, Julia Uffenorde, Oliver Gimm, Mohammad Ali Hosseinpour Feizi, Luiz Lehmann Coutinho, Carlos Guerrero‐Bosagna   +6 more
wiley   +1 more source

Examples of user algorithms implementing ARAIM techniques for integrity performance prediction, procedures development and pre-flight operations [PDF]

, 2016
Advanced Receiver Autonomous Integrity Monitoring (ARAIM) is a new Aircraft Based Augmentation System (ABAS) technique, firstly presented in the two reports of the GNSS Evolutionary Architecture Study (GEAS). The ARAIM technique offers the opportunity to
S. Paternostro, C. Hill, Atkin, Jason, H.P. Morvan, G. De Maere, T. Moore, Moore, Terry, Morvan, Herve, J. Atkin, Paternostro, S., de Maere, Geert, Hill, Chris   +11 more
core   +1 more source

Characterizing and Modeling the BDS-3 Time Group Delay Error for ARAIM

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In the BDS-3 constellation, only the B3I signal is used to compute the broadcast clock offset. However, because advanced receiver autonomous integrity monitoring (ARAIM) uses dual-frequency measurements, the time group delay (TGD) must be considered in ...
Hengwei Zhang, Yiping Jiang, Zhipeng Wang   +2 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source