Results 31 to 40 of about 216,825 (268)

Advanced reactor models for plutonium multirecycling scenario studies using artificial neural networks

EPJ Nuclear Sciences & Technologies
This paper presents an innovative way to identify the plutonium content in MOX fresh fuel according to its isotopic composition in fuel cycle dynamic simulations.
Eveillard Sarah, Courtin Fanny, Doligez Xavier, Ernoult Marc, Thiollière Nicolas, Tirel Kévin, Vidal Jean-François   +6 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Lightweighting cost impacts on market adoption and GHG emissions in U.S. light-duty vehicle fleet

Environmental Research Communications
Vehicle lightweighting is a promising strategy that can reduce energy consumption and GHG emissions without compromising vehicle’s performance or size.
Fan Yang, Aaron Brooker, Sarah Kleinbaum, David Gotthold   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Formation of analytical activity scenarios

Sistemnì Doslìdženâ ta Informacìjnì Tehnologìï, 2014
Advanced analytics is one of the most required information technologies. Research of a scenario formation process of analytical activity is required for advanced analytics realization.
О. V. Koval, К. А. Zaitseva, Yu. D. Boyko   +2 more
doaj  

Enhancing Ship Propulsion Efficiency Predictions with Integrated Physics and Machine Learning

Journal of Marine Science and Engineering
This research develops a dual physics-based machine learning system to forecast fuel consumption and CO2 emissions for a 100 m oil tanker across six operational scenarios: Original, Paint, Advanced Propeller, Fin, Bulbous Bow, and Combined.
Hamid Reza Soltani Motlagh, Seyed Behbood Issa-Zadeh, Md Redzuan Zoolfakar, Claudia Lizette Garay-Rondero   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source