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Venous Leg Ulcers: Advanced Therapies and New Technologies
Biomedicines, 2021 The prevalence of venous leg ulcers (VLUs) differs between 1.5% and 3% in the general population. The challenge in treating VLUs is common recurrence. Moreover, VLUs can be resistant to healing, despite appropriate treatment.
Agnieszka Owczarczyk-Saczonek
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Advances in Thrombolytic Therapy
Drug Intelligence & Clinical Pharmacy, 1982Streptokinase and urokinase are the two thrombolytic agents currently available in the United States. These drugs promote dissolution of thrombi by stimulating the conversion of plasminogen to plasmin, resulting in an overall “lytic state” in the blood. Recent clinical trials in patients with pulmonary emboli, deep vein thrombosis, arterial thrombosis,
D M, Rutkowski, W S, Burkle
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Advances in antiplatelet therapy
Expert Opinion on Emerging Drugs, 2003Cardiovascular diseases (CVDs) are the leading cause of morbidity and mortality in the western world. These disorders share a common pathophysiology -- atherosclerosis, which affects various arterial beds, leading to protean manifestations (coronary artery disease [CAD], stroke, peripheral arterial disease [PAD]).
Hani, Jneid, Deepak L, Bhatt
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Advances in Immunosuppressive Therapy
Seminars in Respiratory and Critical Care Medicine, 2007Despite the intense interest in biological agents, traditional immunosuppressive drugs remain the mainstays of treatment for systemic rheumatic diseases that involve the lung. Herewith, we review the mechanism of action, administration and clinical use of immunosuppressive drugs, including cyclophosphamide, chlorambucil, azathioprine, methotrexate ...
Wendy, Marder, W Joseph, McCune
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Dermatologic Clinics, 2005
Infections with five of the herpesviruses (herpes simplex virus 1 [HSV-1], HSV-2, varicella zoster virus, Epstein-Barr virus, and cytomegalovirus) are treated with topical or systemic antiviral therapies. There are more than 100 genotypes of human papillomaviruses (HPVs), which may manifest as warts, skin cancers, cervical cancer, anogenital cancers ...
Jashin J, Wu +3 more
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Infections with five of the herpesviruses (herpes simplex virus 1 [HSV-1], HSV-2, varicella zoster virus, Epstein-Barr virus, and cytomegalovirus) are treated with topical or systemic antiviral therapies. There are more than 100 genotypes of human papillomaviruses (HPVs), which may manifest as warts, skin cancers, cervical cancer, anogenital cancers ...
Jashin J, Wu +3 more
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Current Opinion in Pediatrics, 1997
For many years, acyclovir has been used to treat herpes simplex and varicella zoster infections in adults and children, although new drugs with improved bioavailability and dosage regimens (ie, famciclovir, valaciclovir) are replacing it for the outpatient management of these conditions in adults.
D E, Dwyer, A M, Kesson
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For many years, acyclovir has been used to treat herpes simplex and varicella zoster infections in adults and children, although new drugs with improved bioavailability and dosage regimens (ie, famciclovir, valaciclovir) are replacing it for the outpatient management of these conditions in adults.
D E, Dwyer, A M, Kesson
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Advances in neuroblastoma therapy
Current Opinion in Pediatrics, 2019Purpose of review Our understanding of the biologic basis of neuroblastoma, the genetic heterogeneity of this malignancy and the role of host factors has expanded significantly in recent years. In this review, we highlight current and future risk-based treatment approaches and discuss the opportunities and challenges of ...
Suzanne, MacFarland, Rochelle, Bagatell
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Advances in antiretroviral therapy
Current Opinion in HIV and AIDS, 2013To review recent data about advances in ART.In the last 2 years, clinical trials have demonstrated the safety and efficacy of three integrase transfer inhibitors [raltegravir (RAL), elvitegravir (EVG) and dolutegravir (DTG)], one new nonnucleoside reverse transcriptase inhibitor [rilpivirine (RIL)] and a new extended release formulation of nevirapine ...
Jose R, Arribas, Joseph, Eron
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Advances in Respiratory Therapy
Veterinary Clinics of North America: Small Animal Practice, 2007Effective respiratory therapy depends on obtaining a definitive diagnosis and following established recommendations for treatment. Unfortunately, many respiratory conditions are idiopathic in origin or are attributable to nonspecific inflammation. In some situations, disorders are controlled rather than cured.
Elizabeth A, Rozanski +2 more
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Advancing therapy for osteosarcoma
Nature Reviews Clinical Oncology, 2021Improving the survival of patients with osteosarcoma has long proved challenging, although the treatment of this disease is on the precipice of advancement. The increasing feasibility of molecular profiling together with the creation of both robust model systems and large, well-annotated tissue banks has led to an increased understanding of ...
Jonathan Gill, Richard Gorlick
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