Treatment With Tumor-infiltrating Lymphocytes in Advanced Melanoma: Evaluation of Early Clinical Implementation of an Advanced Therapy Medicinal Product. [PDF]
J Immunother, 2018 Tumor-infiltrating lymphocytes (TIL)-therapy in advanced melanoma is an advanced therapy medicinal product (ATMP) which, despite promising results, has not been implemented widely.
Lindenberg MA +5 more
europepmc +3 more sources
Hematology, Transfusion and Cell Therapy, 2021 Advanced therapy medicinal products, considered special medications, requires Anvisa approval for use and commercialization in Brazil. They include the advanced cellular therapy products, tissue engineering products and gene therapy products, which due ...
João Batista Silva Junior +4 more
doaj +1 more source
Advanced therapy medicinal products:a comprehensive overview for pharmacy professionals [PDF]
, 2022 An overview of the clinical, institutional, regulatory, safety and economic considerations of advanced therapy medicinal ...
Guy, Richard +6 more
core +1 more source
Gene therapy randomised clinical trials in Europe – a review paper of methodology and design
Journal of Market Access & Health Policy, 2020 Purpose: Gene therapy brings opportunities to discover cures for diseases for which there are no adequate treatments. As most gene therapies target rare diseases, several challenges are associated with their clinical development, such as limited ...
Krassimira Ilieva +2 more
doaj +1 more source
Surgery Versus ATMPs: An Example From Ophthalmology
Frontiers in Bioengineering and Biotechnology, 2020 Advanced therapy medicinal products (ATMPs) are the new frontier of medicine. Advanced therapy medicinal products are set out to satisfy unmet medical needs and provide new innovative, cutting-edge therapies for serious or life-threatening diseases, thus
Federica M. Magrelli +3 more
doaj +1 more source
Advanced therapy medicinal products: current and future perspectives [PDF]
Journal of Market Access & Health Policy, 2016 Advanced therapy medicinal products (ATMPs) are innovative therapies that encompass gene therapy, somatic cell therapy, and tissue-engineered products. These therapies are expected to bring important health benefits, but also to substantially impact the pharmaceuticals budget.The aim of this study was to characterise the ATMPs in development and ...
Hanna, Eve +3 more
openaire +2 more sources
Recombinant PBP2a/autolysin conjugate as PLGA-based nanovaccine induced humoral responses with opsonophagocytosis activity, and protection versus methicillin-resistant Staphylococcus aureus infection [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Methicillin-resistant Staphylococcus aureus (MRSA) reasons extreme infections, can resist various conventional antimicrobial agents, and cause morbidity and mortality worldwide.
Setareh Haghighat +3 more
doaj +1 more source
Preclinical good laboratory practice-compliant safety study to evaluate biodistribution and tumorigenicity of a cartilage advanced therapy medicinal product (ATMP). [PDF]
J Transl Med, 2015 Background: The clinical development of advanced therapy medicinal products (ATMPs), a new class of drugs, requires initial safety studies that deviate from standard non-clinical safety protocols.
Zscharnack M +11 more
europepmc +4 more sources
Advanced Therapy Medicinal Products and the Changing Role of Academia
Transfusion Medicine and Hemotherapy, 2022 Academic institutions coin the ATMP landscape but do not possess an industry-like capacity to vigorously pursue the full developmental pathway to marketing authorization. At the same time, industry has fostered clinical trials with ATMPs, brought the first products to marketing authorization, and defined novel modes of interaction with academia.
Christoph, Priesner, Martin, Hildebrandt
openaire +2 more sources
Candidiasis in breast cancer: Tumor progression or not? [PDF]
Iranian Journal of Basic Medical SciencesCandida albicans is an “opportunistic fungal agent” in cancer patients that can become colonized in both mucosal and deep tissues and cause severe infections. Most evidence has shown that C.
Somayeh Ashrafi +10 more
doaj +1 more source