Results 41 to 50 of about 7,116,245 (266)

Advanced Therapy Medicinal Products Challenges and Perspectives in Regenerative Medicine

Journal of Clinical Medicine Research, 2020
Recently, the design and development of a modern health policy in the field of regenerative medicine leads to the formation of a new and integrated cognitive field, which requires systematic research and study in order to produce innovative answers and best practices.
Goula, Aspasia, Gkioka, Vasiliki, Michalopoulos, Efstathios, Katsimpoulas, Michalis, Noutsias, Michel, Sarri, Eirini Faidra, Stavropoulos, Catherine, Kostakis, Alkiviadis   +7 more
openaire   +3 more sources

The Marketing Authorisation of Advanced Therapy Medicinal Products under the regulation of the European Union

, 2023
International audienceAdvanced Therapy Medicinal Products (ATMPs) is a European classification of medicinal products based on genes, cells and tissues specifically regulated in the European Union (EU) from the entry into force of Regulation (EC) No 1394 ...
Delage, Auxane, Nègre, Olivier, Mahalatchimy, Aurélie, Gilbert, Luc-Sylvain   +3 more
core   +3 more sources

European Regulatory Tools for Advanced Therapy Medicinal Products [PDF]

Transfusion Medicine and Hemotherapy, 2013
Increasing scientific knowledge and technical innovations in the areas of cell biology, biotechnology and medicine resulted in the development of promising therapeutic approaches for the prevention and treatment of human diseases. Advanced therapy medicinal products (ATMPs) reflect a complex and innovative class of bio-pharmaceuticals as these products
Egbert, Flory, Jens, Reinhardt
openaire   +2 more sources

Herbal products: Marketing strategies and legislation [PDF]

, 2009
Marketing of herbal products in the European Union (EU) has been regulated under national legislation for years, leading to differences in legal status of these herbal products.
Hooyenga, P.A., Witkamp, R.F., Groen, K.P.   +2 more
core   +1 more source

Allogenic mesenchymal stromal cells and their extracellular vesicles in COVID-19 induced ARDS: a randomized controlled trial

Stem Cell Research & Therapy, 2023
Background and aims The main causes of death in patients with severe Coronavirus disease-2019 (COVID-19) are acute respiratory distress syndrome (ARDS) and multiorgan failure caused by a severe inflammatory cascade.
Morteza Zarrabi, Mohammad Amin Shahrbaf, Masoumeh Nouri, Faezeh Shekari, Seyedeh-Esmat Hosseini, Seyed-Mohammad Reza Hashemian, Rasoul Aliannejad, Hamidreza Jamaati, Naghmeh Khavandgar, Hediyeh Alemi, Hoda Madani, Abdoreza Nazari, Azadeh Amini, Seyedeh Nafiseh Hassani, Fatemeh Abbasi, Neda Jarooghi, Nasrin Fallah, Leila Taghiyar, Meysam Ganjibakhsh, Ensiyeh Hajizadeh-Saffar, Massoud Vosough, Hossein Baharvand   +21 more
doaj   +1 more source

Propelling Healthcare with Advanced Therapy Medicinal Products: A Policy Discussion [PDF]

Biomedicine Hub, 2020
Recent advances in biomedicine are opening the door to new approaches, and treatment and prevention are being transformed by novel medicines based on genetic engineering, innovative cell-based therapies and tissue-engineered products, and combinations of a medical device with embedded cell or tissue components. These advanced therapy medicinal products
Horgan, Denis, Metspalu, Andres, Ouillade, Marie-Christine, Athanasiou, Dimitrios, Pasi, John, Adjali, Oumeya, Harrison, Patrick, Hermans, Cedric, Codacci-Pisanelli, Giovanni, Koeva, Jasmina, Szucs, Thomas, Cursaru, Viorica, Belina, Ivica, Bernini, Chiara, Zhuang, Suijie, McMahon, Stephen, Toncheva, Draga, Thum, Thomas   +17 more
openaire   +3 more sources

Chemical exposure and alveolar macrophages responses: ‘the role of pulmonary defense mechanism in inhalation injuries’

BMJ Open Respiratory Research, 2023
Epidemiological and clinical studies have indicated an association between particulate matter (PM) exposure and acute and chronic pulmonary inflammation, which may be registered as increased mortality and morbidity.
Mahtab Tapak, Somaye Sadeghi, Tooba Ghazanfari, Nariman Mosaffa   +3 more
doaj   +1 more source

Translational research on advanced therapies

Annali dell'Istituto Superiore di Sanità, 2011
Fostering translational research of advanced therapies has become a major priority of both scientific community and national governments. Advanced therapy medicinal products (ATMP) are a new medicinal product category comprising gene therapy and cell ...
Filippo Belardelli, Paola Rizza, Franca Moretti, Cintia Carella, Maria Cristina Galli, Giovanni Migliaccio   +5 more
doaj   +1 more source

Mitigating Deficiencies in Evidence during Regulatory Assessments of Advanced Therapies: A Comparative Study with Other Biologicals

Molecular Therapy: Methods & Clinical Development, 2020
Advanced therapy medicinal products (ATMPs) comprising cell therapy, gene therapy, and tissue-engineered products, offer a multitude of novel therapeutic approaches to a wide range of severe and debilitating diseases.
Magdi Elsallab, Christopher A. Bravery, Andreas Kurtz, Mohamed Abou-El-Enein   +3 more
doaj   +1 more source

Establishing of human induced pluripotent stem cell line DMSCi002-A from the hematopoietic stem cells of a healthy male donor

Stem Cell Research
Using the integration-free episomal vector containing the reprogramming components OCT3/4/shp53, Sox2/KLF4, L-MYC/LIN28, and EBNA-1, hematopoietic stem cells obtained from a healthy 33-year-old man were effectively reprogrammed and turned into induced ...
Kobkaew Bumroongthai, Chonlada Yodtup, Danai Jantapalaboon, Panapat Phairoh, Supaporn Suparak, Panadda Dhepakson, Alisa Tubsuwan, Sudarat Wongkidakarn   +7 more
doaj   +1 more source