Results 31 to 40 of about 7,093,593 (187)

ATMP Environmental Exposure Assessment in European Healthcare Settings: A Systematic Review of the Literature

Frontiers in Medicine, 2021
Since 2007, a new class of biologic products for human use called “advanced therapy medicinal products (ATMP)” have been legally integrated in the European Medical Agency. They consist of recombinant nucleic acid, engineered cells, cells, or tissues.
Margaux Damerval, Christine Fagnoni-Legat, Aurélien Louvrier, Aurélien Louvrier, Sarah Fischer, Samuel Limat, Samuel Limat, Anne-Laure Clairet, Virginie Nerich, Virginie Nerich, Isabelle Madelaine, Marie Kroemer, Marie Kroemer   +12 more
doaj   +1 more source

Context-Aware Process Modelling for Medicinal Product Development [PDF]

, 2021
Advanced Therapy Medicinal Products (ATMPs) are highly innovative medicinal products that are based on biomedical technology. ATMP development processes need to comply with complex regulatory frameworks.
Stirna, J., Serral, E., Ozturk Yurt, Zeynep, Wilbik, Anna, Ralyté, J., Eshuis, Rik, Vanderfeesten, Irene T. P., Grabis, J.   +7 more
core   +1 more source

Allogenic mesenchymal stromal cells and their extracellular vesicles in COVID-19 induced ARDS: a randomized controlled trial

Stem Cell Research & Therapy, 2023
Background and aims The main causes of death in patients with severe Coronavirus disease-2019 (COVID-19) are acute respiratory distress syndrome (ARDS) and multiorgan failure caused by a severe inflammatory cascade.
Morteza Zarrabi, Mohammad Amin Shahrbaf, Masoumeh Nouri, Faezeh Shekari, Seyedeh-Esmat Hosseini, Seyed-Mohammad Reza Hashemian, Rasoul Aliannejad, Hamidreza Jamaati, Naghmeh Khavandgar, Hediyeh Alemi, Hoda Madani, Abdoreza Nazari, Azadeh Amini, Seyedeh Nafiseh Hassani, Fatemeh Abbasi, Neda Jarooghi, Nasrin Fallah, Leila Taghiyar, Meysam Ganjibakhsh, Ensiyeh Hajizadeh-Saffar, Massoud Vosough, Hossein Baharvand   +21 more
doaj   +1 more source

Magnetically Driven Biofabrication for Tissue Engineering: From Nanoparticle Design to Mag-ATMP Translation. [PDF]

Adv Healthc Mater
Magnetically responsive nanoparticles enable remote control over biomaterials, cells, and engineered tissues. This review summarizes material design, biological safety, fabrication and actuation strategies, computational validation, and translational pathways that support the development of magnetic tissue‐engineering platforms and future magnetically ...
Ioannidis K, Lefas D, Guilliams M, Van Grootenbril J, Decoene I, Sakellariou D, Smeets B, Mourdikoudis S, Papantoniou I.   +8 more
europepmc   +2 more sources

Chemical exposure and alveolar macrophages responses: ‘the role of pulmonary defense mechanism in inhalation injuries’

BMJ Open Respiratory Research, 2023
Epidemiological and clinical studies have indicated an association between particulate matter (PM) exposure and acute and chronic pulmonary inflammation, which may be registered as increased mortality and morbidity.
Mahtab Tapak, Somaye Sadeghi, Tooba Ghazanfari, Nariman Mosaffa   +3 more
doaj   +1 more source

Recombinant PBP2a/autolysin conjugate as PLGA-based nanovaccine induced humoral responses with opsonophagocytosis activity, and protection versus methicillin-resistant Staphylococcus aureus infection [PDF]

Iranian Journal of Basic Medical Sciences, 2022
Objective(s): Methicillin-resistant Staphylococcus aureus (MRSA) reasons extreme infections, can resist various conventional antimicrobial agents, and cause morbidity and mortality worldwide.
Setareh Haghighat, Seyed Davar Siadat, Abbas Akhavan Sepahi, Mehdi Mahdavi   +3 more
doaj   +1 more source

Advanced Therapy Medicinal Products

, 2023
125In recent years advances in biology, biotechnology, and medical research have led to a new category of biologicals – the advanced therapy medicinal products (ATMPs).
Dehmel, Susann, Neuhaus, Vanessa, Schaudien, Dirk   +2 more
core   +1 more source

Advanced therapy medicinal products: what's in a name? [PDF]

, 2020
In this commentary I briefly discuss the term advanced therapy medicinal products (ATMPs). The last two words, medicinal products, correctly indicate that we are dealing with medicines.
Jiskoot, W.
core   +1 more source

Candidiasis in breast cancer: Tumor progression or not? [PDF]

Iranian Journal of Basic Medical Sciences
Candida albicans is an “opportunistic fungal agent” in cancer patients that can become colonized in both mucosal and deep tissues and cause severe infections. Most evidence has shown that C.
Somayeh Ashrafi, Abbas Ali Amini, Pegah Karimi, Maryam Bagherian, Mohammad Mahdi Adibzadeh Sereshgi, Fatemeh Asgarhalvaei, Khadijeh Ahmadi, Mohammad Hossein Yazdi, Hamidreza Jahantigh, Mehdi Mahdavi, Ramin Sarrami Forooshani   +10 more
doaj   +1 more source

Process data of allogeneic ex vivo-expanded ABCB5+ mesenchymal stromal cells for human use: off-the-shelf GMP-manufactured donor-independent ATMP

Stem Cell Research & Therapy, 2020
Background Human dermal mesenchymal stromal cells (MSCs) expressing the ATP-binding cassette (ABC) efflux transporter ABCB5 represent an easily accessible MSC population that, based on preclinical and first-in-human data, holds significant promise to ...
Seda Ballikaya, Samar Sadeghi, Elke Niebergall-Roth, Laura Nimtz, Jens Frindert, Alexandra Norrick, Nicole Stemler, Nicole Bauer, Yvonne Rosche, Vanessa Kratzenberg, Julia Pieper, Tina Ficek, Markus H. Frank, Christoph Ganss, Jasmina Esterlechner, Mark A. Kluth   +15 more
doaj   +1 more source