Results 171 to 180 of about 161,336 (304)

Investigating the impact of adventure education on children's physical, cognitive and socio-emotional development: A mixed method systematic review. [PDF]

PLoS One
A Ghani RB, Lau PWC, Lu N, Zhou P, Wang JJ.   +4 more
europepmc   +1 more source

Choose your own adventure: A perspective on career development. [PDF]

J Clin Transl Sci, 2023
Stanfill AG, Martin MY.
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Virtual Reality as RESPITE: Relief Exploration for Sickle Pain Through Interventions Using Technology Engagement: A Hospital-Based Observational Study. [PDF]

J Gen Intern Med
Vidyasagar N, Nguyen M, Bundy A, Baker NA, Kenj Halabi D, Arora VM, Meltzer DO, Press VG.   +7 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

End of the first decade of EHJ CVP. [PDF]

Eur Heart J Cardiovasc Pharmacother
Agewall S.
europepmc   +1 more source

\u3cb\u3e\u3cem\u3eDoctor Who: Shada: The Lost Adventure by Douglas Adams\u3c/em\u3e\u3c/b\u3e, by Gareth Roberts, Ace, 2012 [PDF]

, 2012
McGrath, James
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Association Between One's Preferred Film Genres and Personality Traits: A Cross-Sectional Study. [PDF]

Cureus
Menon AS, M S C, Naidu S, Chowdary ND.
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source