Results 41 to 50 of about 211,753 (383)

Suspected Adverse Drug Reactions Related to Breast Cancer Chemotherapy: Disproportionality Analysis of the Brazilian Spontaneous Reporting System

Frontiers in Pharmacology, 2019
Spontaneous reporting systems may generate a large volume of information in real world conditions with a relatively low cost. Disproportionality measures are useful to indicate and quantify unexpected safety issues associated with a given drug-event pair
Flávia Campos Barcelos, Guacira Corrêa de Matos, Mario Jorge Sobreira da Silva, Fabrício Alves Barbosa da Silva, Elisangela da Costa Lima   +4 more
doaj   +1 more source

Statistical Analysis System of Spontaneous Adverse Drug Reaction Reports

Journal of Korean Society for Clinical Pharmacology and Therapeutics, 2012
Background: Spontaneous adverse drug reaction (ADR) reporting data has been used for safety of post-market drug surveillance. A system has been required that is able to detect signals associated with drugs by analyzing the collected ADR data. Methods: We developed the web-based automated analysis system (ADR-detector).
Sira Kim, Boram Wang, Jungsun Lee, Bori Kim, Hyeno La, Young Min Park, Inyoung Choi   +6 more
openaire   +1 more source

Effectiveness of interventions to improve adverse drug reaction reporting by healthcare professionals over the last decade: A systematic review

Pharmacoepidemiology and Drug Safety, 2019
Various strategies have been studied in the literature to address the significant underreporting of adverse drug reactions (ADRs) in healthcare systems worldwide.
Raymond Li, S. T. Zaidi, Timothy Chen, R. Castelino   +3 more
semanticscholar   +1 more source

Artificial Intelligence for Unstructured Healthcare Data: Application to Coding of Patient Reporting of Adverse Drug Reactions

Clinical pharmacology and therapy, 2021
Adverse drug reaction (ADR) reporting is a major component of drug safety monitoring; its input will, however, only be optimized if systems can manage to deal with its tremendous flow of information, based primarily on unstructured text fields.
L. Létinier, Julien Jouganous, M. Benkebil, Alicia Bel-Létoile, C. Goehrs, Allison Singier, Franck Rouby, Clémence Lacroix, G. Miremont, J. Micallef, F. Salvo, A. Pariente   +11 more
semanticscholar   +1 more source

Integrating pharmacovigilance into the routine of pharmacy department: experience of nine years [PDF]

Farmacia Hospitalaria, 2019
Objective: To describe our pharmacovigilance program and to analyze the reported adverse drug reactions. Method: Observational longitudinal study conducted from 2008 to 2016.
Ariadna Pérez-Ricart, Elvira Gea-Rodríguez, Ana Roca-Montañana, Esperanza Gil-Máñez, Amanda Pérez-Feliu   +4 more
doaj   +1 more source

Knowledge of Adverse Drug Reaction Reporting and the Pharmacovigilance of Biological Medicines: A Survey of Healthcare Professionals in Ireland

BioDrugs, 2018
In Europe, changes to pharmacovigilance legislation, which include additional monitoring of medicines, aim to optimise adverse drug reaction (ADR) reporting systems.
Joan O’Callaghan, B. Griffin, J. M. Morris, M. Bermingham   +3 more
semanticscholar   +1 more source

Disclosure and adverse effects of complementary and alternative medicine used by hospitalized patients in the North East of England [PDF]

, 2012
Objectives: This study aimed to investigate the prevalence, disclosure and adverse effects of complementary and alternative medicine (CAM) use in hospitalised patients, and to explore the associations between patients’ perceived side-effects and relevant
Baqir, wasim, Bello, Nusirat, McGarry, Kenneth, Winit -Watjana, Win   +3 more
core   +2 more sources

Complementing the US Food and Drug Administration Adverse Event Reporting System With Adverse Drug Reaction Reporting From Social Media: Comparative Analysis [PDF]

JMIR Public Health and Surveillance, 2020
Background Adverse drug reactions (ADRs) can occur any time someone uses a medication. ADRs are systematically tracked and cataloged, with varying degrees of success, in order to better understand their etiology and develop methods of prevention.
Zeyun Zhou, Kyle Emerson Hultgren
openaire   +5 more sources

Evidence and Extrapolation: Mechanisms for Regulating Off-Label Uses of Drugs and Devices [PDF]

, 2014
A recurring, foundational issue for evidence-based regulation is deciding whether to extend governmental approval from an existing use with sufficient current evidence of safety and efficacy to a novel use for which such evidence is currently lacking ...
Abbott, Ryan, Ayres, Ian
core   +3 more sources

Analysis of Adverse Drug Reactions to First-Line Anti-Tuberculosis Drugs Using the Korea Adverse Event Reporting System

Journal of Korean Medical Science, 2022
Adverse drug reactions (ADRs) to first-line anti-tuberculosis (TB) drugs are common; however, there have been few reports of nationwide epidemiologic studies on ADRs to anti-TB drugs in Korea. This study aimed to investigate the clinical characteristics of various ADRs to first-line anti-TB drugs using a nationwide database of ADRs.We used the Korea ...
Soo Jie Chung, Sun-ju Byeon, Jeong-Hee Choi   +2 more
openaire   +2 more sources