Results 41 to 50 of about 860,145 (127)

Pattern and quality of scientific communications on drug safety produced by a regional pharmacovigilance center in Nepal

Pharmacy Practice, 2010
Analyzing the pattern and quality of scientific communications on pharmacovigilance can help the regional centers in Nepal and other developing countries to develop approaches for communicating effectively medicine safety issues. This kind of research is
Palaian S, Ibrahim MIM, Mishra P
doaj  

Evolução e elementos-chave do sistema de farmacovigilância do Brasil: uma revisão de escopo a partir da criação da Agência Nacional de Vigilância Sanitária

Cadernos de Saúde Pública, 2018
Esta revisão de escopo objetiva descrever e caracterizar o sistema de farmacovigilância do Brasil (SINAF) e averiguar o atendimento aos requisitos mínimos propostos pela Organização Mundial da Saúde para um desempenho funcional de sistemas nacionais ...
Daniel Marques Mota, Álvaro Vigo, Ricardo de Souza Kuchenbecker   +2 more
doaj   +1 more source

Intensive Monitoring Studies for Assessing Medicines: A Systematic Review

Frontiers in Medicine, 2019
Introduction: Intensive monitoring (IM) is one of the methods of post-marketing active surveillance based upon event monitoring, which has received interest in the current medicines regulatory landscape. For a specific period of time, IM involves primary
Carla Torre, Carla Torre, Maria Cary, Fábio Cardoso Borges, Paula S. Ferreira, Paula S. Ferreira, Joana Alarcão, Hubert G. Leufkens, João Costa, João Costa, Ana Paula Martins   +10 more
doaj   +1 more source

HODDI: A Dataset of High-Order Drug-Drug Interactions for Computational Pharmacovigilance [PDF]

arXiv
Drug-side effect research is vital for understanding adverse reactions arising in complex multi-drug therapies. However, the scarcity of higher-order datasets that capture the combinatorial effects of multiple drugs severely limits progress in this field. Existing resources such as TWOSIDES primarily focus on pairwise interactions.
arxiv  

An Overview of Clinical Pharmacology of Ibuprofen

Oman Medical Journal, 2010
Ibuprofen was the first member of Propionic acid derivatives introduced in 1969. It is a popular domestic and over the counter analgesic and antipyretic for adults and children.
Nousheen Aslam, Rabia Bushra
doaj  

BICEPP: an example-based statistical text mining method for predicting the binary characteristics of drugs

BMC Bioinformatics, 2011
Background The identification of drug characteristics is a clinically important task, but it requires much expert knowledge and consumes substantial resources.
Tsafnat Guy, Polasek Thomas M, Anthony Stephen, Lin Frank PY, Doogue Matthew P   +4 more
doaj   +1 more source

Research on Adverse Drug Reaction Prediction Model Combining Knowledge Graph Embedding and Deep Learning [PDF]

arXiv
In clinical treatment, identifying potential adverse reactions of drugs can help assist doctors in making medication decisions. In response to the problems in previous studies that features are high-dimensional and sparse, independent prediction models need to be constructed for each adverse reaction of drugs, and the prediction accuracy is low, this ...
arxiv  

Leg amputation following intramuscular injection of iron dextran in a 32 year old woman

Journal of Pharmaceutical Care, 2015
To inform healthcare professionals of a rare serious reaction leading to leg amputation following intramuscular injection of iron dextran and report comments for preventing such reactions.A case of leg amputation following intramuscular injection of iron
Gloria Shalviri, Kheirollah Gholami, Naghmeh Javidnikou   +2 more
doaj  

Spontaneous adverse drug reactions reported in a thirteen-year pharmacovigilance program in a tertiary university hospital

Frontiers in Pharmacology
ObjectivesWe aimed to assess the characteristics of adverse drug reactions (ADRs) collected in a university hospital.MethodsA retrospective analysis of ADRs spontaneously reported in the Hospital Pharmacovigilance Program database (RutiRAM) over a 13 ...
E. Montané, E. Montané, Y. Sanz, S. Martin, C. Pérez-Mañá, C. Pérez-Mañá, E. Papaseit, E. Papaseit, O. Hladun, G. De la Rosa, M. Farré, M. Farré   +11 more
doaj   +1 more source

Detecting adverse high-order drug interactions from individual case safety reports using computational statistics on disproportionality measures [PDF]

arXiv
Adverse drug interactions are a critical concern in pharmacovigilance, as both clinical trials and spontaneous reporting systems often lack the breadth to detect complex drug interactions. This study introduces a computational framework for adverse drug interaction detection, leveraging disproportionality analysis on individual case safety reports.
arxiv