Results 61 to 70 of about 38,036 (299)

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

Statistical Analysis System of Spontaneous Adverse Drug Reaction Reports

Journal of Korean Society for Clinical Pharmacology and Therapeutics, 2012
Background: Spontaneous adverse drug reaction (ADR) reporting data has been used for safety of post-market drug surveillance. A system has been required that is able to detect signals associated with drugs by analyzing the collected ADR data. Methods: We developed the web-based automated analysis system (ADR-detector).
Sira Kim, Boram Wang, Jungsun Lee, Bori Kim, Hyeno La, Young Min Park, Inyoung Choi   +6 more
openaire   +1 more source

A Multi-Agent System for Reporting Suspected Adverse Drug Reactions

Online Journal of Public Health Informatics, 2014
Adverse drug reactions (ADRs) represent a serious worldwide public health problem. Current post-marketing ADR detection approaches largely rely on spontaneous reports filed by various healthcare professionals such as physicians, pharmacists et.al.. Underreporting is a serious deficiency of these methods - the actually reported adverse events represent ...
Yanqing Ji, Fangyang Shen, See-Yan Lau, John Tran   +3 more
openaire   +2 more sources

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Adverse drug reactions reported for systemic antibacterials in Danish children over a decade [PDF]

British Journal of Clinical Pharmacology, 2010
Systemic antibacterials are among the most frequently prescribed drugs in children to treat respiratory tract infections [1, 2]. Empirical studies have shown that Danish children receive more broad-spectrum penicillins compared with children in Italy, Canada and Scandinavia [3–5].
Aagaard, Lise, Hansen, Ebba Holme
openaire   +3 more sources

Pharmacovigilance and drug safety 2011 in Calabria (Italy): Adverse events analysis

Journal of Research in Medical Sciences, 2012
Background : Pharmacovigilance assesses the safety profile of drugs. Its main aim is the increase of spontaneous reporting of adverse drug reactions (ADRs). The Italian Drug Agency (AIFA; Agenzia Italiana del Farmaco) is financing several projects to the
Francesca Scicchitano, Chiara Giofrè, Caterina Palleria, Carmela Mazzitello, Miriam Ciriaco, Luca Gallelli, Laura Paletta, Giuseppina Marrazzo, Salvatore De Fazio, Michele Menniti, Rubens Curia, Concetta Arena, Serafina Chimirri, Marinella Patanè, Stefania Esposito, Felisa Cilurzo, Orietta Staltari, Emilio Russo, Giovambattista De Sarro   +18 more
doaj  

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Yellow Fever Virus Vaccine–associated Deaths in Young Women

Emerging Infectious Diseases, 2011
Yellow fever vaccine–associated viscerotropic disease is a rare sequela of live-attenuated virus vaccine. Elderly persons and persons who have had thymectomies have increased susceptibility.
Stephen J. Seligman
doaj   +1 more source

Pharmacovigilance:pharmacists' perspective on spontaneous adverse drug reaction reporting [PDF]

, 2017
Globally, adverse drug reactions (ADRs), one of the leading causes of morbidity and mortality, will continue to pose a threat to public health as long as drugs are being used to treat various ailments.
Zin, Rosdi M, Chin Fen Neoh, Ejaz Cheema, Muhammad Abdul Hadi, Elrggal, Mahmoud E, Mahmoud Elrggal, Hadi, Muhammad Abdul, Rosdi M. Zin, Cheema, Ejaz, Neoh, Chin Fen   +9 more
core   +1 more source