Results 41 to 50 of about 38,036 (299)

“Adverse Drug Reaction Reporting” Knowledge, Attitude and Practices of Community Pharmacy Dispensers in Dar es salaam, Tanzania [PDF]

, 2011
Under reporting of adverse drug reactions (ADRs) by healthcare personnel is a common problem of many Pharmacovigilence programs. Lack of involvement of healthcare professionals such as pharmacists and other pharmaceutical dispensers has been cited as one
Shimwela, Grace Mng’ong’o
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Morbidity and Mortality Weekly Report (MMWR) [PDF]

High levels of coverage with safe and effective immunizations are critical to the successful control and Prevention of vaccine-preventable Diseases Worldwide.

core   +4 more sources

Exposure to potential drug-antimicrobial agent interactions in primary health care [PDF]

Vojnosanitetski Pregled, 2018
Background/Aim. Drug-drug interactions involving antimicrobials present important and often unrecognized complications of pharmacotherapy which can be prevented.
Nikolić Božana, Popović Jovan, Bećarević Mirjana, Rakić Dušica   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Reacciones adversas a medicamentos en una población colombiana, 2007-2013: análisis de bases de datos

Biomédica: revista del Instituto Nacional de Salud, 2016
Introducción. La detección de las reacciones adversas a medicamentos es cada vez más importante en la práctica clínica. Objetivo. Determinar la frecuencia de reacciones adversas a medicamentos y de los casos sospechosos de tales reacciones, en la ...
Jorge Enrique Machado-Alba, Manuel José Londoño-Builes, Luis Felipe Echeverri-Cataño, Sergio Andrés Ochoa-Orozco   +3 more
doaj   +1 more source

On the assessment of adverse drug reactions from spontaneous reporting systems: the influence of under‐reporting on odds ratios

Statistics in Medicine, 2002
AbstractA well‐known problem in spontaneous reporting systems (SRSs) for adverse drug reactions (ADRs) is under‐reporting, that is, the problem that not all occurrences of ADRs are reported to the SRS. We look at the question of how to draw statistical conclusions from analyses of SRS data using reporting odds ratios.
Heijden, P.G.M. van der, Puijenbroek, E.P. van, Buuren, S. van, Hofstede, J.W. van der   +3 more
openaire   +8 more sources

Doctor of Pharmacy [PDF]

, 1984
dissertationIn July 1979, in accordance with the Joint Commission on Accreditation of Hospitals (JCAH) standards, the Pharmacy and Therapeutics Committee approved a policy for reporting adverse drug reactions (ADRs) occurring within the 370-bed ...
Nightingale, James Barrett
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source