Results 51 to 60 of about 13,793,115 (299)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
, 1984 dissertationIn July 1979, in accordance with the Joint Commission on Accreditation of Hospitals (JCAH) standards, the Pharmacy and Therapeutics Committee approved a policy for reporting adverse drug reactions (ADRs) occurring within the 370-bed ...
Nightingale, James Barrett
core
Adverse drug reactions in neonates: a brief analysis of the FDA adverse event reporting system
Frontiers in PharmacologyIntroductionDrug trials in neonates are scarce, and the neonates may consequently be at risk of adverse drug reactions (ADRs). Spontaneous ADR reporting is an important tool for expanding the knowledge on drug safety in neonates. This study explores the quality of current neonatal ADR reports and the ADR reports of the most common drugs used in ...
Pernille Kähler Byskov +10 more
openaire +5 more sources
An introduction to adverse drug reaction reporting systems in different countries
International Journal of Pharmacy Practice, 2005 Abstract Objective To review adverse drug reaction (ADR) reporting schemes in selected developed countries, with emphasis on identifying community pharmacists' roles in ADR reporting. Setting International comparison between eight ...
Reza, S.M.R., Emmerton, L.M.
openaire +4 more sources
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Awareness among nurses about reporting of adverse drug reactions in Sweden
Drug, Healthcare and Patient Safety, 2012 Elisabet Ekman,1–3 Göran Petersson,2 Sven Tågerud,3 Martin Bäckström41Regional Pharmacovigilance Unit, R & D Centre Skåne, Skåne University Hospital, Lund, 2eHealth Institute ...
Ekman E +3 more
doaj
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
Nurses as adverse drug reaction reporting advocates [PDF]
, 2022 Adverse drug reactions (ADRs) is a challenge in modern healthcare, particularly given the increasing complexity of drug therapy, an ageing population, rising multimorbidity, and a high patient turnover.
Pettersen, Trond Røed +3 more
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FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source