Results 21 to 30 of about 289,227 (263)

Ranking Adverse Drug Reactions With Crowdsourcing

Journal of Medical Internet Research, 2015
BackgroundThere is no publicly available resource that provides the relative severity of adverse drug reactions (ADRs). Such a resource would be useful for several applications, including assessment of the risks and benefits of drugs and improvement of ...
Gottlieb, Assaf, Hoehndorf, Robert, Dumontier, Michel, Altman, Russ B   +3 more
doaj   +1 more source

Pharmacovigilance of Severe Cutaneous Adverse Drug Reactions

Clinical Dermatology Review, 2022
Background: Severe cutaneous adverse drug reactions (SCARs) are idiosyncratic reactions comprising 2% of all drug-induced skin reactions. These include Stevens–Johnson syndrome (SJS), toxic epidermal necrolysis, drug reaction with eosinophilia and ...
Kriteeka Saini, Amita Sutaria, Bela Shah
doaj   +1 more source

Age-Associated Risk of Liver-Related Adverse Drug Reactions

Frontiers in Medicine, 2022
ObjectiveAging population is generally considered more sensitive to adverse drug reactions (ADRs). Yet, big data-based quantitative evidence currently does not exist to support this concept.
Yan-zhong Han, Yan-zhong Han, Yu-ming Guo, Peng Xiong, Fei-lin Ge, Jing Jing, Ming Niu, Xu Zhao, Zhao-fang Bai, Hai-bo Song, Xiao-he Xiao, Jia-bo Wang, Jia-bo Wang   +12 more
doaj   +1 more source

Severe adverse drug reactions [PDF]

Clinical Medicine, 2016
Severe cutaneous adverse reactions (SCARs) can present in a multitude of ways including Stevens-Johnson syndrome, toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms, and acute generalised exanthematous pustulosis. While the prognosis and therapy for these conditions may vary, it is crucial that the culprit drug is ...
Ying Xin, Teo, Sarah Anne, Walsh
openaire   +2 more sources

Dermoscopic Aspects of Cutaneous Adverse Drug Reactions

Dermatology Practical & Conceptual, 2021
Background: Little is known about the dermoscopic evaluation of cutaneous adverse drug reactions (CADRs). Objectives: To evaluate the dermoscopic patterns of CADRs and identify those associated with severe cutaneous adverse reactions to drugs (SCARDs).
Gabriela Rossi, André da Silva Cartell, Renato Marchiori Bakos   +2 more
doaj   +1 more source

Children and ADRs (Adverse Drug Reactions)

Italian Journal of Pediatrics, 2010
Many medicines are prescribed to the paediatric population on an unlicensed or 'off-label' basis because they have not been adequately tested and/or formulated and authorized for use in appropriate paediatric age groups.
Napoleone Ettore
doaj   +1 more source

Pharmacovigilance of Antiretroviral Drugs at B.P. Koirala Institute of Health sciences

Journal of Nepal Health Research Council, 2021
Background: Antiretroviral drugs are lifeline for patients living with HIV. Adverse drug reactions can compromise the compliance to antiretroviral therapy.
Deependra Prasad Sarraf, Gajendra Prasad Rauniar, Roshan Chhetri, Shyam Prasad Kafle, Suchana Marahatta, Basudha Khanal, Sanjib Kumar Sharma, Vivek Kattel   +7 more
doaj   +1 more source

HLA‐associated adverse drug reactions ‐ scoping review

Clinical and Translational Science, 2021
Alleles of the human leukocyte antigen (HLA) system have been associated with the occurrence of idiosyncratic adverse drug reactions (ADRs). Accordingly, it is assumed that pre‐emptive testing for the presence of certain HLA alleles (HLA‐typing) could ...
Chiara Jeiziner, Ursina Wernli, Katja Suter, Kurt E. Hersberger, Henriette E. Meyer zu Schwabedissen   +4 more
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Adverse drug reactions in self-medication [PDF]

Саратовский научно-медицинский журнал, 2012
The research goal is to study the actual problem of self-medication. The Association of the European Self-Medication Industry (AESGP) considers the term «responsible self-medication».
Smuseva O.N., Solovkina Yu.V.
doaj