Results 81 to 90 of about 3,233,551 (309)

Suppressor nozzle and airframe noise measurements during flyover of a modified F106B aircraft with underwing nacelles [PDF]

open access: yes
The effect of flight velocity on the jet noise and thrust of a 104-tube suppressor nozzle was investigated using an F-106B delta wing aircraft modified to carry two underwing nacelles each containing a turbojet engine.
Burley, R. R.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Health care resource use and costs associated with possible side effects of high oral corticosteroid use in asthma: a claims-based analysis

open access: yesClinicoEconomics and Outcomes Research, 2016
Allan T Luskin,1 Evgeniya N Antonova,2 Michael S Broder,3 Eunice Y Chang,3 Theodore A Omachi,2 Dennis K Ledford4 1HealthyAirways, Madison, WI, 2Genentech, Inc., South San Francisco, 3Partnership for Health Analytic Research, LLC, Beverly Hills, CA ...
Luskin AT   +5 more
doaj  

The Effects of the Minimum Wage in the Private and Public Sectors in Brazil [PDF]

open access: yes
The wage and employment effects of the minimum wage predicted by the standard neoclassical theory rely on a profit maximizing firm, not on a Government employer that can cover the higher wage bill by raising taxes, reducing expenditure, or simply ...
Sara lemos
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Adverse Selection and Financial Crises [PDF]

open access: yes
The recent financial crisis has highlighted the importance of adverse selection as a contributing factor to financial market instability. In this article, the author examines the phenomenon of adverse selection and explains how its presence in a ...
Koralai Kirabaeva
core  

Rolofylline, an adenosine A1−receptor antagonist, in acute heart failure [PDF]

open access: yes, 2010
Background: Worsening renal function, which is associated with adverse outcomes, often develops in patients with acute heart failure. Experimental and clinical studies suggest that counterregulatory responses mediated by adenosine may be involved. We
Bloomfield, Daniel M   +15 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Does Aid Mitigate External Shocks? [PDF]

open access: yes
This paper investigates the role of aid in mitigating the adverse effects of commodity export price shocks on growth in commodity-dependent countries. Using a large cross-country dataset, we find that negative shocks matter for short-term growth, while ...
Collier, Paul, Goderis, Benedikt
core   +3 more sources

Safety of Annona muricata Extract Supplementation for Colorectal Cancer Patients

open access: yesThe Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2016
Background: People have used Annona muricata leaves traditionally as tea drinks. Traditional use of A. muricata leaves is as an infusion which is closed to water extract. The potential health benefit of A.
Lili Indrawati   +4 more
doaj  

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