Results 81 to 90 of about 3,341,525 (390)
Vascular endothelial‐cadherin as a marker of endothelial injury in preclinical Alzheimer disease
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1926-1940, December 2022., 2022 Abstract Objective Endothelial dysfunction is an early and prevalent pathology in Alzheimer disease (AD). We here investigate the value of vascular endothelial‐cadherin (VEC) as a cerebrospinal fluid (CSF) marker of endothelial injury in preclinical AD.
Rawan Tarawneh +5 more
wiley +1 more source
Frontiers in Microbiology, 2019 Treatment of Mycobacterium abscessus pulmonary infection requires long-term administration of multiple antibiotics. Little is known, however, about the impact of each antibiotic on treatment outcomes.
Jianhui Chen +13 more
doaj +1 more source
Effect of weather conditions on airport operations [PDF]
, 1979 The effect of adverse weather on airport operations are discussed.
Ginty, D. F.
core +1 more source
Molecular Oncology, EarlyView.Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa +13 more
wiley +1 more source
A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1985-1998, December 2022., 2022 Abstract Objectives Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy.
Aina Calls +9 more
wiley +1 more source
Hyperuricemia, use of antituberculosis drugs, and liver injury: case report
Jurnal Teknologi Laboratorium, 2023 Anti-tuberculous drug can cause idiosyncratic drug-induced liver injury (DILI). Considering the benefit risk, there will discontinuation therapy and rechallenge after symptom resolve.
Vina Yuwantari +9 more
doaj +1 more source
Generating Clear Images From Images With Distortions Caused by Adverse Weather Using Generative Adversarial Networks [PDF]
arXiv, 2022 We presented a method for improving computer vision tasks on images affected by adverse weather conditions, including distortions caused by adherent raindrops. Overcoming the challenge of applying computer vision to images affected by adverse weather conditions is essential for autonomous vehicles utilizing RGB cameras.
arxiv
Bullying, Education and Labour Market Outcomes: Evidence from the National Child Development Study [PDF]
, 2005 We explore the effect of bullying at school on the educational attainment of a sample of individuals drawn from the British National Child Development Study (NCDS).
Brown, S., Taylor, K.
core
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, EarlyView.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Molecular Oncology, EarlyView.CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar +4 more
wiley +1 more source