Results 61 to 70 of about 15,484,713 (310)

Adverse Effects of Low-Dose Methotrexate

Annals of Internal Medicine, 2020
Background Low-dose methotrexate (LD-MTX) is the most commonly used drug for systemic rheumatic diseases worldwide and is the recommended first-line agent for rheumatoid arthritis.
D. Solomon, R. Glynn, E. Karlson, Fengxin Lu, Cassandra Corrigan, J. Colls, Chang Xu, Jean G Macfadyen, M. Barbhaiya, N. Berliner, P. Dellaripa, Brendan M. Everett, A. Pradhan, S. Hammond, M. Murray, Deepak A. Rao, S. Ritter, Anna E. Rutherford, J. Sparks, J. Stratton, Dong-Hyun Suh, S. Tedeschi, K. Vanni, N. Paynter, P. Ridker   +24 more
semanticscholar   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

Green rush and red warnings: Retrospective chart review of adverse events of interactions between cannabinoids and psychotropic drugs

Frontiers in Pharmacology
AimOur objective was to systematically assess the prevalence and clinical features of adverse events related to interactions between cannabinoids and psychotropic drugs through a retrospective chart review.Methodology1586 adverse event reports were ...
Adrian Andrzej Chrobak, Jarosław Woroń, Jarosław Woroń, Jarosław Woroń, Marcin Siwek   +4 more
doaj   +1 more source

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka, Tsukuru Amano, Akimasa Takahashi, Mari Deguchi, Hiroyuki Yamanaka, Yuji Tanaka, Shunichiro Tsuji, Takashi Murakami   +7 more
wiley   +1 more source

Allergy to penicillin and betalactam antibiotics

Einstein (São Paulo)
Betalactams are the most frequent cause of hypersensitivity reactions to drugs mediated by a specific immune mechanism. Immediate reactions occur within 1 to 6 hours after betalactam administration, and are generally IgE-mediated.
Mara Morelo Rocha Felix, Marcelo Vivolo Aun, Ullissis Pádua de Menezes, Gladys Reis e Silva de Queiroz, Adriana Teixeira Rodrigues, Ana Carolina D’Onofrio-Silva, Maria Inês Perelló, Inês Cristina Camelo-Nunes, Maria Fernanda Malaman   +8 more
doaj   +2 more sources

Upacicalcet: A Novel Intravenous Calcimimetic Agent for Patients Undergoing Hemodialysis With Secondary Hyperparathyroidism

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa, Daisuke Honda, Seigo Akari, Tadao Akizawa   +3 more
wiley   +1 more source

Recommendations for the use of opioids in Brazil: Part IV. Adverse opioid effects

Revista Dor
BACKGROUND AND OBJECTIVES:Adequate opioid use in the short and long term, as well as diagnosis, management of adverse effects, abuse and chemical dependence of such agents are still an investigation area for many researchers.
Durval Campos Kraychete, João Batista Santos Garcia, José Tadeu Tesseroli de Siqueira   +2 more
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda, Tomohiro Saito, Masahide Mizobuchi, Tomoki Shimomura, Saki Kawamori, Mitsuru Kawanishi, Natsuko Hattori, Jo Sugiyama, Satoshi Tsubata, Hanami Horiguchi, Kazuki Abe, Nao Iida, Yuki Kajio, Nao Oguro, Ryo Yanai, Hirokazu Honda   +15 more
wiley   +1 more source

Benefits and Adverse Effects of Histidine Supplementation.

Journal of NutriLife, 2020
Histidine is a nutritionally essential amino acid with many recognized benefits to human health, while circulating concentrations of histidine decline in pathologic conditions [e.g., chronic obstructive pulmonary disease (COPD) and chronic kidney disease
A. Thalacker-Mercer, Mary E Gheller
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source