Results 101 to 110 of about 3,194,674 (312)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Safety assessment of gemtuzumab ozogamicin: real-world adverse event analysis based on the FDA Adverse Event Reporting System

Frontiers in Medicine
ObjectiveTo mine adverse drug events (ADEs) following the use of gemtuzumab ozogamicin based on the FDA Adverse Event Reporting System (FAERS), and to provide references for the safety assessment of clinical drug use.MethodsWe obtained reports of adverse
Xuexue Liu, Fang Wu, Zhuoyan Li, Chenxi Li, Xinyu Li, Yining Yuan, Xinyu Sun, Ying Du, Xiao Du, Siliang Wang, Peipei Xu   +10 more
doaj   +1 more source

Intervention to improve adverse event reporting in the emergency department: Protocol of a systematic review and meta-analysis. [PDF]

BackgroundAdverse event reporting is crucial for improving patient safety and identifying areas for improvement in the emergency department. Many interventions have been employed in that regard, and have been found to increase adverse event reporting ...
Adelaide Maria Ansah Ofei, Ofei, Adelaide MariaAnsah, Atswei Adzo Kwashie, Collins Atta Poku, Kwashie, Atswei Adzo, Jonathan Bayuo, Poku, Collins Atta, Bayuo, Jonathan   +7 more
core   +1 more source

Correlation between vaccine type and adverse event frequency.

, 2020
Correlation between vaccine type and adverse event frequency.
Keiichi Mikasa (4953835), Mitsuru Konishi (8616699), Taku Ogawa (5492183), Kei Kasahara (3613949), Takashi Inoue (178378)   +4 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

The Adverse Event Paradox

Philosophy of Medicine, 2022
Thomas Milovac
doaj   +1 more source

Supplemental Material, Table_S1 - Comparison of Serious Adverse Event Profiles Among Antirheumatic Agents Using Japanese Adverse Drug Event Report Database

, 2018
Supplemental Material, Table_S1 for Comparison of Serious Adverse Event Profiles Among Antirheumatic Agents Using Japanese Adverse Drug Event Report Database by Yomei Matsuoka, Mamoru Narukawa in Therapeutic Innovation & Regulatory Science
Mamoru Narukawa (5170892), Yomei Matsuoka (5170889)   +1 more
core   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Supplemental Material, Table_S3 - Comparison of Serious Adverse Event Profiles Among Antirheumatic Agents Using Japanese Adverse Drug Event Report Database

, 2018
Supplemental Material, Table_S3 for Comparison of Serious Adverse Event Profiles Among Antirheumatic Agents Using Japanese Adverse Drug Event Report Database by Yomei Matsuoka, Mamoru Narukawa in Therapeutic Innovation & Regulatory Science
Mamoru Narukawa (5170892), Yomei Matsuoka (5170889)   +1 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source