Results 91 to 100 of about 278,304 (313)

Risks and benefits of psychotropic medication in pregnancy: cohort studies based on UK electronic primary care health records

Health Technology Assessment, 2016
Background: Although many women treated with psychotropic medication become pregnant, no psychotropic medication has been licensed for use in pregnancy. This leaves women and their health-care professionals in a treatment dilemma, as they need to balance
Irene Petersen, Rachel L McCrea, Cormac J Sammon, David PJ Osborn, Stephen J Evans, Phillip J Cowen, Nick Freemantle, Irwin Nazareth   +7 more
doaj   +1 more source

Improved maternal–fetal outcomes among emergency obstetric referrals following phone call communication at a teaching hospital in south western Uganda: a quasi-experimental study

BMC Pregnancy and Childbirth, 2022
Background Emergency obstetric referrals develop adverse maternal–fetal outcomes partly due to delays in offering appropriate care at referral hospitals especially in resource limited settings.
Hamson Kanyesigye, Jerome Kabakyenga, Edgar Mulogo, Yarine Fajardo, Daniel Atwine, Noni E. MacDonald, Robert Bortolussi, Richard Migisha, Joseph Ngonzi   +8 more
doaj   +1 more source

Prediction of adverse maternal outcomes in pre-eclampsia: development and validation of the fullPIERS model. [PDF]

, 2011
BACKGROUND: Pre-eclampsia is a leading cause of maternal deaths. These deaths mainly result from eclampsia, uncontrolled hypertension, or systemic inflammation.
Ansermino, JM, Broughton Pipkin, F, Côté, AM, Douglas, MJ, Gruslin, A, Hutcheon, JA, Joseph, KS, Kyle, PM, Lee, SK, Lee, T, Li, J, Loughna, P, Magee, LA, Menzies, JM, Merialdi, M, Millman, AL, Moore, MP, Moutquin, JM, Ouellet, AB, Payne, B, PIERS Study Group, PIERS, Russell, JA, Smith, GN, von Dadelszen, P, Walker, JJ, Walley, KR, Walters, BN, Widmer, M   +27 more
core   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

The use of the Edmonton Obesity Staging System compared to body mass index to predict adverse pregnancy outcomes

Pregnancy
Background In nonpregnant populations, obesity staging systems such as the Edmonton Obesity Staging System (EOSS) improve risk stratification of patients with obesity by also accounting for medical comorbidities.
Sarah E. White, David M. Stamilio
doaj   +1 more source

Trial protocol OPPTIMUM : does progesterone prophylaxis for the prevention of preterm labour improve outcome? [PDF]

, 2012
Background Preterm birth is a global problem, with a prevalence of 8 to 12% depending on location. Several large trials and systematic reviews have shown progestogens to be effective in preventing or delaying preterm birth in selected high risk women ...
A Shennan, American College of Obstetricians and Gynecologists, Andrew Shennan, Anon, AT Northen, BAPM/RCPCH Working Group Report, D Farine, D Wolke, EB da Fonseca, EB Fonseca, H Honest, IR Edwards, Jane E Norman, JE Norman, JM Dodd, JM Dodd, John Norrie, L Sanchez-Ramos, M Arbyn, M Junpeng, March of Dimes Foundation, N Modi, Neil Marlow, Neil Sebire, PA Lachenbruch, Phillip Bennett, PJ Meis, R Romero, RL Goldenberg, RN Hoover, S Kenyon, SL Kenyon, Sonia Whyte, SS Hassan, Stavros Petrou, Stephen Robson, Steven Thornton, Tina Lavender   +37 more
core   +5 more sources

Hierarchical Channeled Graphitized Nanoarchitecture as a Diagnostic Platform for Maternal Fever Warning

Advanced Science, EarlyView.
This study presents a hierarchically channeled graphitized nanoarchitecture (HPGC‐Z67) as a novel nano‐diagnostic platform. It enables sensitive and efficient N‐glycan extraction from plasma, significantly reducing processing time and cost. The platform identifies pivotal N‐glycans to accurately differentiate between infectious and non‐infectious ...
Yiwen Lin, Ning Li, Heyuhan Zhang, Xufang Hu, Zhiqiang Liu, Chunhui Deng   +5 more
wiley   +1 more source

Maternal obesity has little effect on the immediate offspring but impacts on the next generation [PDF]

, 2013
Maternal obesity during pregnancy has been linked to an increased risk of obesity and cardiometabolic disease in the offspring, a phenomenon attributed to developmental programming. Programming effects may be transmissible across generations through both
Dakin, Rachel S., Drake, Amanda J., Hadoke, Patrick W. F., King, Vicky, Liu, Lincoln, Norman, Jane E., Seckl, Jonathan R., Walker, Brian R.   +7 more
core   +1 more source

Navigating an STI diagnosis: The role of social support, intergenerational learning, and transformative growth among Black women

American Journal of Community Psychology, EarlyView.
Abstract Black women face a myriad of challenges that heighten their susceptibility to sexually transmitted infections (STIs), resulting in a disproportionate impact of STIs among this population. Yet, there is a lack of research that explores how women navigate these diagnoses with resilience.
Jaleah D. Rutledge, Jasmine Abrams, Ijeoma Opara, Robin Lin Miller   +3 more
wiley   +1 more source

Effect of implementation of the MOREOB program on adverse maternal and neonatal birth outcomes in Ontario, Canada: a retrospective cohort study

BMC Pregnancy and Childbirth, 2019
Background In 2002, the MOREOB (Managing Obstetrical Risk Efficiently) obstetrical patient safety program was phased-in across hospitals in Ontario, Canada.
Deborah Weiss, Deshayne B. Fell, Ann E. Sprague, Mark C. Walker, Sandra Dunn, Jessica Reszel, Wendy E. Peterson, Doug Coyle, Monica Taljaard   +8 more
doaj   +1 more source