Results 101 to 110 of about 2,016,996 (294)

Management of Pregnancy in Women of Advanced Maternal Age: Improving Outcomes for Mother and Baby

open access: yesInternational Journal of Women's Health, 2021
Itamar Glick,1 Ela Kadish,2 Misgav Rottenstreich1,3 1Department of Obstetrics & Gynecology, Shaare Zedek Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel; 2Faculty of Medicine, Hebrew University of Jerusalem ...
Glick I, Kadish E, Rottenstreich M
doaj  

An Adverse Outcome Pathway for Potential Space Radiation Induced Neurological Diseases [PDF]

open access: yes
Astronauts have begun to spend increasingly longer periods in space, putting themselves in foreign environments in order to explore the unknown. Space radiation is one of the largest health risks faced by astronauts on their missions. The space radiation
Mi, Kaitlyn, Norman, Ryan B.
core   +1 more source

Weight changes following lower limb arthroplasty : a prospective observational study [PDF]

open access: yes, 2009
The aim of this study was to assess patterns of weight loss/gain following total hip or knee joint replacement. Four hundred and fifty primary lower limb arthroplasty patients, where the current surgery was the last limiting factor to improved mobility ...
Abu-Rajab, R.B.   +4 more
core  

Impact of elosulfase alfa in patients with morquio A syndrome who have limited ambulation: An open-label, phase 2 study. [PDF]

open access: yes, 2017
Efficacy and safety of elosulfase alfa enzyme replacement therapy (ERT) were assessed in an open-label, phase 2, multi-national study in Morquio A patients aged ≥5 years unable to walk ≥30 meters in the 6-min walk test.
Berger, Kenneth I   +11 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Management of Pregnancy in Women of Advanced Maternal Age: Improving Outcomes for Mother and Baby [Corrigendum]

open access: yesInternational Journal of Women's Health, 2023
Glick I, Kadish E, Rottenstreich M. Int J Womens Health. 2021;13:751-759. Page 756, Autism Spectrum Disorder section, second paragraph, first sentence, the text “A large meta-analysis, including 16 epidemiological papers with 5687 autism spectrum ...
Glick I, Kadish E, Rottenstreich M
doaj  

Metabolomics Discovers Early-Response Metabolic Biomarkers that Can Predict Chronic Reproductive Fitness in Individual Daphnia magna

open access: yesMetabolites, 2018
Chemical risk assessment remains entrenched in chronic toxicity tests that set safety thresholds based on animal pathology or fitness. Chronic tests are resource expensive and lack mechanistic insight. Discovering a chemical’s mode-of-action can in
Nadine S. Taylor   +2 more
doaj   +1 more source

High dose rate brachytherapy as monotherapy for localised prostate cancer : a hypofractionated two-implant approach in 351 consecutive patients [PDF]

open access: yes, 2013
BACKGROUND: To report the clinical outcome of high dose rate brachytherapy as sole treatment for clinically localised prostate cancer. METHODS: Between March 2004 and January 2008, a total of 351 consecutive patients with clinically localised prostate ...
Baltas, Dimos   +6 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Risk factors for failure of outpatient parenteral antibiotic therapy (OPAT) in infective endocarditis [PDF]

open access: yes, 2013
Objectives: To identify risk factors for failure of outpatient antibiotic therapy (OPAT) in infective endocarditis (IE). Patients and methods: We identified IE cases managed at a single centre over 12 years from a prospectively maintained database. ‘
Barr, D. A.   +5 more
core   +1 more source

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